Evidence map›Paper›PMID 37524993›Full record

ArticleJournal of anesthesia2023

Prediction of anesthetic torsadogenicity using a human ventricular cell model.

Akiko Kojima, Yutaka Fukushima, Hiroshi Matsuura

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of anesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Akiko KojimaDepartment of Anesthesiology, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan. akiko77@belle.shiga-med.ac.jp.ORCID 0000-0002-9649-5495
Yutaka FukushimaDepartment of Anesthesiology, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan.
Hiroshi MatsuuraDepartment of Physiology, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan.

Funding

Japan Society for the Promotion of Science 20K09195
6 · The paper itself

Abstract

This simulation study was designed to predict the torsadogenicity of sevoflurane and propofol in healthy control, as well as type 1 and type 2 long QT syndrome (LQT1 and LQT2, respectively), using the O'Hara-Rudy dynamic model. LQT1 and LQT2 models were simulated by decreasing the conductances of slowly and rapidly activating delayed rectifier K

Indexed as

AnestheticsLong QT SyndromePropofolAction PotentialsHumansSevofluraneAnestheticsPropofolSevofluraneHuman ventricular cell modelI KrI KsLong QT syndromeTorsadogenicity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.