ArticleClinical research in cardiology : official journal of the German Cardiac Society2024
Feasibility and outcome of third-generation transcatheter aortic valve implantation in patients with extra-large aortic annulus.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Managing Aortic Regurgitation and Dynamic Aortic Thrombus in a Patient With Left Ventricular Assist Device.JACC. Case reports · 2026Article
- Outcomes of surgical and transcatheter aortic valve replacement in patients with large and extra-large aortic annuli.JTCVS open · 2026Article
- Transcatheter Aortic Valve Implantation in a Massive Aortic Annulus With a Novel Balloon-Expandable Valve.JACC. Case reports · 2026Article
- Performance of XL Sizes of Myval Balloon-Expandable Valve in Real-World Patients with Extremely Large Aortic Annuli.Medicina (Kaunas, Lithuania) · 2026Observational
- Swimming in the OCEAN-TAVI of Large Annulus.JACC. Asia · 2024Article
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Authors and funding
15 authors.
Funding
Abstract
backgroundMany patients in need for transcatheter aortic valve implantation (TAVI) present with an aortic annulus size larger than recommended by the manufacturer's instructions for use (IFU).
aimsTo investigate procedural and short-term safety and efficacy of TAVI in patients with extra-large annuli (ELA).
methods30-day clinical outcome and valve performance as defined by VARC 3 of 144 patients with an aortic annulus size exceeding the permitted range were compared to a propensity-score matched control cohort of patients with an aortic annulus size consistent with the IFU.
resultsArea and perimeter was 730.4 ± 53.9 mm
conclusionTreatment of ELA patients with third-generation TAVI prostheses is feasible and safe, providing similar device success and complication rates as in matched controls with regular-sized aortic annulus. Post-interventional pacemaker implantation rates were low compared to the control group, yet incidence of moderate PVL remains problematic in ELA patients.
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