Evidence map›Paper›PMID 37524757›Full record

ReviewNature reviews. Microbiology2024

Insights into the assembly and regulation of the bacterial divisome.

Todd A Cameron, William Margolin

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Defining the order of assembly of theJournal of bacteriology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Control of cell division by anbioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Defining the order of assembly of thebioRxiv : the preprint server for biology · 2026
    Article
  18. MemPrO: A Predictive Tool for Membrane Protein Orientation.Journal of chemical theory and computation · 2026
    Article
  19. Review
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Todd A CameronDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, TX, USA.ORCID http://orcid.org/0000-0002-6608-6551
William MargolinDepartment of Microbiology and Molecular Genetics, McGovern Medical School, Houston, TX, USA. william.margolin@uth.tmc.edu.ORCID http://orcid.org/0000-0001-6557-7706

Funding

Mechanisms and Regulation of Cell Division in BacteriaR35GM131705 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WILLIAM MARGOLIN · 2019 to 2026
$3.8M
NIGMS NIH HHS R35 GM131705
6 · The paper itself

Abstract

The ability to split one cell into two is fundamental to all life, and many bacteria can accomplish this feat several times per hour with high accuracy. Most bacteria call on an ancient homologue of tubulin, called FtsZ, to localize and organize the cell division machinery, the divisome, into a ring-like structure at the cell midpoint. The divisome includes numerous other proteins, often including an actin homologue (FtsA), that interact with each other at the cytoplasmic membrane. Once assembled, the protein complexes that comprise the dynamic divisome coordinate membrane constriction with synthesis of a division septum, but only after overcoming checkpoints mediated by specialized protein-protein interactions. In this Review, we summarize the most recent evidence showing how the divisome proteins of Escherichia coli assemble at the cell midpoint, interact with each other and regulate activation of septum synthesis. We also briefly discuss the potential of divisome proteins as novel antibiotic targets.

Indexed as

Escherichia coli ProteinsBacteriaBacterial ProteinsCytoskeletal ProteinsEscherichia coliBacterial ProteinsCytoskeletal ProteinsEscherichia coli Proteins

Identifiers

PMID37524757
PMCPMC11102604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.