Evidence map›Paper›PMID 37524391›Full record

ArticleThorax2023

Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study.

Constantinos Kallis, Ekaterina Maslova, Ann D Morgan, Ian Sinha, Graham Roberts, Ralf J P van der Valk, Jennifer K Quint, Trung N Tran

Open access · hybridAbstract read
In one paragraph

Article in Thorax, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Oscillometry for the diagnosis of asthma in children: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Observational
  3. Article
  4. Early Origins of Asthma and Allergies: Clues From Studies in China.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Constantinos KallisFaculty of Medicine, National Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0003-0866-5421
Ekaterina MaslovaBioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.ORCID 0000-0001-5415-8119
Ann D MorganFaculty of Medicine, National Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0003-4794-0860
Ian SinhaAlder Hey Children's Hospital, Liverpool, UK.
Graham RobertsUniversity of Southampton Faculty of Medicine, Southampton, UK.ORCID 0000-0003-2252-1248
Ralf J P van der ValkBioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.ORCID 0000-0002-3052-2796
Jennifer K QuintFaculty of Medicine, National Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0003-0149-4869
Trung N TranBiopharmaceuticals Medical, Respiratory and Immunology, AstraZeneca, Gaithersburg, Maryland, USA trung.tran1@astrazeneca.com.ORCID 0000-0001-8003-7601
Imperial College London · GBAstraZeneca (United Kingdom) · GBAstraZeneca (France) · FRUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma-related burden remains poorly characterised in children in the UK. We quantified recent trends in asthma prevalence and burden in a UK population-based cohort (1‒17-year-olds).

methodsThe Clinical Practice Research Datalink Aurum database (2008‒2018) was used to assess annual asthma incidence and prevalence in 1‒17-year-olds and preschool wheeze in 1‒5-year-olds, stratified by sex and age. During the same period, annual asthma exacerbation rates were assessed in those with either a diagnosis of preschool wheeze or asthma.

resultsAnnual asthma incidence rates decreased by 51% from 1403.4 (95% CI 1383.7 to 1423.2) in 2008 to 688.0 (95% CI 676.3 to 699.9) per 10

conclusionPaediatric asthma incidence decreased in the UK since 2008, particularly in 1-5-year-olds; this was accompanied by a decline in asthma prevalence. Preschool wheeze incidence also decreased in this age group. However, exacerbation rates have been increasing.

Indexed as

AsthmaAdolescentChildChild, PreschoolHumansIncidencePrevalenceRespiratory SoundsAsthma EpidemiologyPaediatric asthma

Identifiers

PMID37524391
PMCPMC10715559
OpenAlexW4385412594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.