ArticleAmerican journal of respiratory and critical care medicine2023
A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
14.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Approach to the Evaluation and Management of Interstitial Lung Abnormalities: An Official American Thoracic Society Clinical Statement.American journal of respiratory and critical care medicine · 2025Guideline
- Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Next-Generation Sequencing in Pulmonary Fibrosis: Translational Promise and Current Clinical Limitations.Current issues in molecular biology · 2026Review
- The Genetic Landscape of Fibrotic Interstitial Lung Diseases: Clinical Implications and Diagnostic Challenges in Familial Pulmonary Fibrosis.Journal of clinical medicine · 2026Review
- Disease Mechanisms and Therapeutic Advances in Idiopathic and Progressive Pulmonary Fibrosis: From Approved Drugs to Emerging Strategies.Journal of clinical medicine · 2026Review
- Ectopic expression of MUC5B in the respiratory bronchiole initiates endoplasmic reticulum stress in the IPF lung.American journal of respiratory cell and molecular biology · 2026Article
- Polygenic risk and rare variants in endotypes of idiopathic pulmonary fibrosis: a genetic analysis of population-based and case-control cohorts.The Lancet. Respiratory medicine · 2026Article
- Relationship between habitual glucosamine use and risk of incident idiopathic pulmonary fibrosis with the modification effect of genetic susceptibility: a prospective cohort study.European journal of nutrition · 2026Article
- Polygenic risk scores: Navigating the future of precision medicine through economic, ethical, and scientific advancements.iScience · 2026Review
- Age-dependent Genetic Risk in Pulmonary Fibrosis Patients and Relatives.medRxiv : the preprint server for health sciences · 2026Article
- NUFIP1 gain of function promotes fibrotic remodeling and reveals a ZNHIT3-linked metabolic vulnerability in idiopathic pulmonary fibrosis models.Frontiers in immunology · 2026Article
- Current diagnosis, epidemiology, and management of interstitial lung abnormalities.Frontiers in medicine · 2026Review
- Interstitial lung abnormalities: a mechanistic window into early fibrotic lung disease.Frontiers in medicine · 2026Review
- Familial interstitial lung disease: emerging insights into screening and genetic risk.Frontiers in medicine · 2026Review
- Genetic Determinants of Progressive Pulmonary Fibrosis: A Comprehensive Review.International journal of molecular sciences · 2025Review
- Genetic Familial Interstitial Lung Disease.Clinics in chest medicine · 2025Review
- Racial, Ethnic, Sex, and Gender Equity for Inclusive Interstitial Lung Disease Research: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Review
- Race, Environmental Exposures, and Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine · 2025Article
- Genetic Associations in Non-Europeans with Pulmonary Fibrosis: Analysis of the All of Us Cohort.American journal of respiratory and critical care medicine · 2025Article
- Sex-specific genetic effects on susceptibility to idiopathic pulmonary fibrosis.ERJ open research · 2025Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
38 authors at 14 institutions in 3 countries.
Matthew MollDivision of Pulmonary and Critical Care Medicine, and.
Anna L PeljtoDepartment of Medicine and.ORCID 0000-0002-8389-0736
John S KimDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, Virginia.
Hanfei XuDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Catherine L DebbanCenter for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, Virginia.
Xianfeng ChenDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Phoenix, Arizona.
Aravind MenonDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-0211-4509
Rachel K PutmanDivision of Pulmonary and Critical Care Medicine, and.
Auyon J GhoshDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, State University of New York Upstate Medical Center, Syracuse, New York.
Aabida SaferaliChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Mizuki NishinoCenter for Pulmonary Functional Imaging, Department of Radiology.
Hiroto HatabuCenter for Pulmonary Functional Imaging, Department of Radiology.
Brian D HobbsDivision of Pulmonary and Critical Care Medicine, and.
Julian HeckerChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Gregory McDermottDivision of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Jeffrey A SparksDivision of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Louise V WainDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Richard J AllenDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Martin D TobinDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Benjamin A RabyChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Sung ChunDivision of Pulmonary Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Edwin K SilvermanDivision of Pulmonary and Critical Care Medicine, and.
Ana C ZamoraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Phoenix, Arizona.
Victor E OrtegaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Phoenix, Arizona.
Christine K GarciaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0002-0771-1249
R Graham BarrDepartment of Medicine and.
Eugene R BleeckerDivision of Genetics, Genomics, and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona.
Deborah A MeyersDivision of Genetics, Genomics, and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona.
Robert J KanerDivision of Pulmonary Medicine, Weill Cornell School of Medicine, New York, New York.
Stephen S RichCenter for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, Virginia.
Ani ManichaikulCenter for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, Virginia.
Jerome I RotterThe Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-University of California, Los Angeles Medical Center, Torrance, California.
Josée DupuisDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
George T O'ConnorDepartment of Medicine, Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts; and.
Tasha E FingerlinThe National Jewish Health Cohen Family Asthma Institute, Division of Allergy and Immunology, National Jewish Health, Denver, Colorado.
Gary M HunninghakeDivision of Pulmonary and Critical Care Medicine, and.
David A SchwartzDepartment of Medicine and.
Michael H ChoDivision of Pulmonary and Critical Care Medicine, and.
Brigham and Women's Hospital · USUniversity of Virginia · USBoston University · USMayo Clinic Hospital · USPulmonary and Critical Care Associates · USUniversity of Leicester · GBColumbia University Irving Medical Center · USUniversity of Arizona · USUniversity of Colorado Anschutz Medical Campus · USBoston Children's Hospital · USCornell University · USNational Jewish Health · USSUNY Upstate Medical University · USUniversity of California, Los Angeles · US
Funding
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1MInstitute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MGenetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9MTransgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILES Frome WILKINSON · 2003 to 2026
$40.4MWake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3MFRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · 2019 to 2024
$29.8MSPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MRespiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9MMechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLACKWELL, TIMOTHY S. · 2010 to 2020
$21.6MGenetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9MBLRD VA I01 BX005295Department of HealthNCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001881NCI NIH HHS R01 CA203636NCI NIH HHS U01 CA209414NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268201000001INHLBI NIH HHS HHSN268201000021CNHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS K01 HL157613NHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08 HL159318NHLBI NIH HHS K23 HL150301NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N02 HL064278NHLBI NIH HHS N02 HL64278NHLBI NIH HHS P01 HL092870NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P01 HL132825NHLBI NIH HHS P01 HL162607NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL111527NHLBI NIH HHS R01 HL117626NHLBI NIH HHS R01 HL120393NHLBI NIH HHS R01 HL121270NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL133135NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL142992NHLBI NIH HHS R01 HL147148NHLBI NIH HHS R01 HL149836NHLBI NIH HHS R01 HL152728NHLBI NIH HHS R01 HL153248NHLBI NIH HHS R01 HL155522NHLBI NIH HHS R01 HL158668NHLBI NIH HHS RC1 HL100543NHLBI NIH HHS T32 HL007427NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NHLBI NIH HHS U01 HL120393NHLBI NIH HHS U01 HL137880NHLBI NIH HHS UG3 HL151865NHLBI NIH HHS UH3 HL151865NIAMS NIH HHS P30 AR070253NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR077607NIAMS NIH HHS R01 AR080659NIAMS NIH HHS T32 AR007530NIDDK NIH HHS P30 DK063491Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
Genome-Wide Association StudyIdiopathic Pulmonary FibrosisGenetic Predisposition to DiseaseHumansLungMucin-5BRisk FactorsMucin-5Bidiopathic pulmonary fibrosisinterstitial lung abnormalitiesMUC5Bpolygenic risk score
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What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.