Evidence map›Paper›PMID 37523711›Full record

ArticleMolecular cancer therapeutics2023

The Cooperative Human Tissue Network of the National Cancer Institute: Supporting Cancer Research for 35 Years.

Shannon J McCall, Irina A Lubensky, Christopher A Moskaluk, Anil Parwani, Kiley Radin, Nilsa C Ramirez, Zachery Von Menchhofen, Mary K Washington, Virginia A LiVolsi

Abstract read
In one paragraph

Article in Molecular cancer therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shannon J McCallDepartment of Pathology, Duke University School of Medicine and Duke Cancer Institute, Durham, North Carolina.ORCID 0000-0003-3957-061X
Irina A LubenskyNCI, NIH, Bethesda, Maryland.ORCID 0000-0002-1374-0695
Christopher A MoskalukDepartment of Pathology, University of Virginia, Charlottesville, Virginia.ORCID 0000-0002-7049-681X
Anil ParwaniDepartment of Pathology, The Ohio State University, Columbus, Ohio.ORCID 0009-0007-7224-6682
Kiley RadinNCI, NIH, Bethesda, Maryland.ORCID 0009-0004-8591-430X
Nilsa C RamirezNationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0002-9945-9449
Zachery Von MenchhofenDepartment of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-0928-3660
Mary K WashingtonDepartment of Pathology, Vanderbilt University, Nashville, Tennessee.ORCID 0000-0002-9589-7695
Virginia A LiVolsiDepartment of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-7035-5259

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
COG U24 Funding 2026-2027U24CA196173 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Mignon Lee-Cheun Loh, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$62.5M
NRG Oncology Biospecimen BankU24CA196067 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Tanner J. Freeman, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$42.6M
SWOG U24 Funding for 2026-2027U24CA196175 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI James Michael Rae, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$37.6M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2019 to 2026
$19.6M
(EET Biobank) NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank - CIMAC SupplementU24CA254445 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Kathleen Nicol, Nilsa Del Carmen Ramirez Milan · 2020 to 2026
$16.5M
PROJECT 3: Applying Liquid Biopsy Technologies to Detect Clinical Response and Mechanisms of Resistance in the Treatment of LMSP50CA272170 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JUDY E. GARBER · 2022 to 2026
$13.3M
Tennessee Valley Cooperative Human Tissue NetworkUM1CA183727 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2014 to 2026
$12.6M
COOPERATIVE HUMAN TISSUE NETWORK EASTERN DIVISIONUM1CA239745 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Kathleen T. Montone · 2019 to 2026
$6.6M
Biospecimen procurement and tissue microarray manufacture for the CHTNUM1CA239752 · NCI · UNIVERSITY OF VIRGINIA · PI Christopher A. Moskaluk · 2019 to 2026
$6.6M
Cooperative Human Tissue Network (CHTN)UM1CA239754 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Nilsa Del Carmen Ramirez Milan · 2019 to 2026
$6.3M
NCI NIH HHS P20 CA251657NCI NIH HHS P30 CA014236NCI NIH HHS P50 CA236733NCI NIH HHS P50 CA272170NCI NIH HHS U24 CA196067NCI NIH HHS U24 CA196173NCI NIH HHS U24 CA196175NCI NIH HHS U24 CA254445NCI NIH HHS UM1 CA183727NCI NIH HHS UM1 CA239745NCI NIH HHS UM1 CA239749NCI NIH HHS UM1 CA239752NCI NIH HHS UM1 CA239754NCI NIH HHS UM1 CA239755NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

The Cooperative Human Tissue Network was created by the NCI in 1987 to support a coordinated national effort to collect and distribute high quality, pathologist-validated human tissues for cancer research. Since then, the network has expanded to provide different types of tissue samples, blood and body fluid samples, immunohistologic and molecular sample preparations, tissue microarrays, and clinical datasets inclusive of biomarkers and molecular testing. From inception through the end of 2021, the network has distributed 1,375,041 biospecimens. It served 889 active investigators in 2021. The network has also taken steps to begin to optimize the representation of diverse communities among the distributed biospecimens. In this article, the authors review the 35-year history of this network, describe changes to the program over the last 15 years, and provide operational and scientific highlights from each of the divisions. Readers will learn how to engage with the network and about the continued evolution of the program for the future.

Indexed as

NeoplasmsBiomarkersHumansNational Cancer Institute (U.S.)United StatesBiomarkers

Identifiers

PMID37523711
PMCPMC10626893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.