Evidence map›Paper›PMID 37523710›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Circulating CC16 and Asthma: A Population-based, Multicohort Study from Early Childhood through Adult Life.

Nipasiri Voraphani, Debra A Stern, Julie G Ledford, Amber L Spangenberg, Jing Zhai, Anne L Wright, Wayne J Morgan, Monica Kraft, Duane L Sherrill, John A Curtin and 11 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Maternal smoking and CC-16: implications for lung development and COPD across the lifespan.American journal of respiratory and critical care medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Towards early detection and disease interception of COPD across the lifespan.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  13. Frequent exacerbator-a novel endotype of pediatric asthma.The Journal of allergy and clinical immunology · 2025
    Review
  14. Article
  15. Article
  16. Frontiers in immunology · 2025
    Article
  17. Review
  18. Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life Course.American journal of respiratory and critical care medicine · 2024
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 4 countries.

Nipasiri VoraphaniAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0003-4526-7975
Debra A SternAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0003-4683-6084
Julie G LedfordAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0001-7977-4575
Amber L SpangenbergAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.
Jing ZhaiAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.
Anne L WrightAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.
Wayne J MorganAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0002-6346-8140
Monica KraftAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.
Duane L SherrillAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.
John A CurtinDivision of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Clare S MurrayDivision of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-8961-8055
Adnan CustovicNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0001-5218-7071
Inger KullDepartment of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Jenny HallbergDepartment of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Anna BergströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; and.
Esther Herrera-LuisGenomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Spain.
Marilyn HalonenAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0001-9606-935X
Fernando D MartinezAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0001-6094-2727
Angela SimpsonDivision of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-2733-6666
Erik MelénDepartment of Clinical Sciences and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-8248-0663
Stefano GuerraAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona.ORCID 0000-0001-7218-3246
University of Arizona · USKarolinska Institutet · SENational Health Service · GBImperial College London · GBUniversidad de La Laguna · ES

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Early Origins of Chronic Lung Disease: Outcomes into the Fifth Decade of LifeR01HL132523 · NHLBI · UNIVERSITY OF ARIZONA · PI Stefano Guerra, Fernando D Martinez · 2016 to 2026
$15.1M
CC16 in Childhood and Resilience to Persistent Asthma into Adult Life (Supplement)R01AI135108 · NIAID · UNIVERSITY OF ARIZONA · PI Stefano Guerra · 2017 to 2026
$5.4M
Defining mechanisms of CC16 on epithelial-driven host responses to pathogensR01HL142769 · NHLBI · UNIVERSITY OF ARIZONA · PI Julie Gunnells Ledford · 2019 to 2026
$4.2M
Serum Biomarkers of COPD: a population-based prospective studyR01HL095021 · NHLBI · UNIVERSITY OF ARIZONA · PI GUERRA, STEFANO · 2009 to 2013
$2.0M
Department of Health NIHR203308Medical Research Council G0601361Medical Research Council MR/K002449/1Medical Research Council MR/K002449/2Medical Research Council MR/L012693/1Medical Research Council MR/S002359/1Medical Research Council MR/S025340/1Medical Research Council MR/T031565/1Medical Research Council MR/W028352/1NHLBI NIH HHS R01 HL095021NHLBI NIH HHS R01 HL132523NHLBI NIH HHS R01 HL142769NIAID NIH HHS R01 AI135108NIEHS NIH HHS P30 ES006694
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaUteroglobinAdolescentAdultChildChild, PreschoolHumansSwedenYoung AdultSCGB1A1 protein, humanUteroglobinasthmabirth cohortsCC16

Identifiers

PMID37523710
PMCPMC10563188
OpenAlexW4385410816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.