Evidence map›Paper›PMID 37523546›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

MBTD1 preserves adult hematopoietic stem cell pool size and function.

Keiyo Takubo, Phyo Wai Htun, Takeshi Ueda, Yasuyuki Sera, Masayuki Iwasaki, Miho Koizumi, Kohei Shiroshita, Hiroshi Kobayashi, Miho Haraguchi, Shintaro Watanuki and 9 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Exploring management of acrodermatitis.Asia Pacific journal of clinical nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 3 countries.

Keiyo TakuboDepartment of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.ORCID 0000-0002-1736-7592
Phyo Wai HtunMedical Department, 7887 Healthcare Call Center, Yangon 11062, Myanmar.
Takeshi UedaDepartment of Biochemistry, Kindai University Faculty of Medicine, Sayama-shi, Osaka 589-8511, Japan.ORCID 0000-0001-9823-6764
Yasuyuki SeraField of Human Disease Models, Major in Advanced Life Sciences and Medicine, Institute of Laboratory Animals, Tokyo Women's Medical University, Shinjuku-ku, Tokyo 162-8666, Japan.
Masayuki IwasakiField of Human Disease Models, Major in Advanced Life Sciences and Medicine, Institute of Laboratory Animals, Tokyo Women's Medical University, Shinjuku-ku, Tokyo 162-8666, Japan.ORCID 0000-0002-3003-3853
Miho KoizumiField of Human Disease Models, Major in Advanced Life Sciences and Medicine, Institute of Laboratory Animals, Tokyo Women's Medical University, Shinjuku-ku, Tokyo 162-8666, Japan.
Kohei ShiroshitaDepartment of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.ORCID 0009-0001-8721-2430
Hiroshi KobayashiDepartment of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.ORCID 0000-0002-0924-1252
Miho HaraguchiDepartment of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
Shintaro WatanukiDepartment of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
Zen-Ichiro HondaHealth Care Center and Graduate School of Humanities and Sciences, Institute of Environmental Science for Human Life, Ochanomizu University, Bunkyo-ku, Tokyo 112-8611, Japan.
Norimasa YamasakiDepartment of Molecular Oncology, Research Institute of Radiation Biology and Medicine, Hiroshima University, Minami-ku, Hiroshima 734-8553, Japan.
Ayako Nakamura-IshizuDepartment of Microscopic and Developmental Anatomy, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Fumio AraiDepartment of Stem Cell Biology and Medicine, Graduate School of Medical Science, Kyusyu University, Fukuoka 812-8582, Japan.ORCID 0000-0003-1936-4907
Noboru MotoyamaDepartment of Human Nutrition, Sugiyama Jogakuen University School of Life Studies, Nagoya 464-8662, Japan.ORCID 0009-0005-4992-2289
Tomohisa HattaMolecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo 135-0064, Japan.
Tohru NatsumeMolecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo 135-0064, Japan.ORCID 0000-0002-1510-2582
Toshio SudaCancer Science Institute of Singapore, National University of Singapore Center for Translational Medicine, Singapore 117599, Singapore.
Hiroaki HondaField of Human Disease Models, Major in Advanced Life Sciences and Medicine, Institute of Laboratory Animals, Tokyo Women's Medical University, Shinjuku-ku, Tokyo 162-8666, Japan.ORCID 0000-0002-4617-9670
National Center for Global Health and Medicine · JPTokyo Women's Medical University · JPNational Institute of Advanced Industrial Science and Technology · JPHiroshima University · JPKindai University · JPMyanmar Oxford Clinical Research Unit · MMNational University of Singapore · SGOchanomizu University · JPSugiyama Jogakuen University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bone MarrowHematopoietic Stem CellsAnimalsCell CycleHematopoiesisMiceMice, Inbred C57BLMice, KnockoutRepressor ProteinsTranscription Factorshemp protein, mouseRepressor ProteinsTranscription FactorsFOXO3ahematopoietic stem cells (HSCs)HSC quiescenceMBTD1 (mbt domain containing 1)

Identifiers

PMID37523546
PMCPMC10410756
OpenAlexW4385409748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.