Evidence map›Paper›PMID 37523308›Full record

ArticleEnvironmental science & technology2023

Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants.

Hesham Amin, Tina Šantl-Temkiv, Christine Cramer, Kai Finster, Francisco Gomez Real, Thorarinn Gislason, Mathias Holm, Christer Janson, Nils Oskar Jögi, Rain Jogi and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Environmental science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. The Indoor Microbiome: Sampling, Analysis and Emerging Trends.Environmental microbiology reports · 2026
    Pooled it
  2. Article
  3. Article
  4. Household cleaning product exposure and severe bronchiolitis in infancy: A case-control study.The journal of allergy and clinical immunology. In practice · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The indoors microbiome and human health.Nature reviews. Microbiology · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 6 countries.

Hesham AminDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0001-9191-506X
Tina Šantl-TemkivSection for Microbiology, Department of Biology, Aarhus University, 8000 Aarhus, Denmark.
Christine CramerDepartment of Public Health, Environment, Work and Health, Danish Ramazzini Center, Aarhus University, 8000 Aarhus, Denmark.
Kai FinsterSection for Microbiology, Department of Biology, Aarhus University, 8000 Aarhus, Denmark.
Francisco Gomez RealDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Thorarinn GislasonFaculty of Medicine, University of Iceland, 102 Reykjavík, Iceland.
Mathias HolmDepartment of Occupational and Environmental Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy, Sleep Research, Uppsala University, 751 85 Uppsala, Sweden.
Nils Oskar JögiDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Rain JogiTartu University Hospital, Lung Clinic, 50406 Tartu, Estonia.
Andrei MalinovschiDepartment of Medical Sciences: Clinical Physiology, Uppsala University, 751 85 Uppsala, Sweden.
Ian P G MarshallSection for Microbiology, Department of Biology, Aarhus University, 8000 Aarhus, Denmark.
Lars ModigDivision of Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, 901 87 Umeå, Sweden.
Dan NorbäckDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, 751 85 Uppsala, Sweden.
Rajesh ShigdelDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Torben SigsgaardDepartment of Public Health, Environment, Work and Health, Danish Ramazzini Center, Aarhus University, 8000 Aarhus, Denmark.
Cecilie SvanesDepartment of Occupational Medicine, Haukeland University Hospital, 5053 Bergen, Norway.
Hulda ThorarinsdottirDepartment of Anesthesia and Intensive Care, Landspitali University Hospital, 101 Reykjavik, Iceland.
Inge M WoutersInstitute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CS Utrecht, The Netherlands.
Vivi SchlünssenDepartment of Public Health, Environment, Work and Health, Danish Ramazzini Center, Aarhus University, 8000 Aarhus, Denmark.
Randi J BertelsenDepartment of Clinical Science, University of Bergen, 5021 Bergen, Norway.
Aarhus University · DKUniversity of Bergen · NOUppsala University · SEHaukeland University Hospital · NOReykjavík University · ISTartu University Hospital · EEUmeå University · SEUniversity of Gothenburg · SEUniversity of Iceland · ISUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airborne bacteria and endotoxin may affect asthma and allergies. However, there is limited understanding of the environmental determinants that influence them. This study investigated the airborne microbiomes in the homes of 1038 participants from five cities in Northern Europe: Aarhus, Bergen, Reykjavik, Tartu, and Uppsala. Airborne dust particles were sampled with electrostatic dust fall collectors (EDCs) from the participants' bedrooms. The dust washed from the EDCs' clothes was used to extract DNA and endotoxin. The DNA extracts were used for quantitative polymerase chain (qPCR) measurement and 16S rRNA gene sequencing, while endotoxin was measured using the kinetic chromogenic limulus amoebocyte lysate (LAL) assay. The results showed that households in Tartu and Aarhus had a higher bacterial load and diversity than those in Bergen and Reykjavik, possibly due to elevated concentrations of outdoor bacterial taxa associated with low precipitation and high wind speeds. Bergen-Tartu had the highest difference (ANOSIM

Indexed as

Air Pollution, IndoorMicrobiotaAnimalsBacteriaDogsDustEndotoxinsRNA, Ribosomal, 16SDustEndotoxinsRNA, Ribosomal, 16S16S rRNA and occupants’ ageairborne microbiomemeteorological dataNorthern Europe

Identifiers

PMID37523308
PMCPMC10433529
OpenAlexW4385415146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.