Evidence map›Paper›PMID 37523103›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2023

Nickel chloride complexes with substituted 4'-phenyl-2',2':6',2″-terpyridine ligands: synthesis, characterization, anti-proliferation activity and biomolecule interactions.

Benwei Wang, Dameng Sun, Sihan Wang, Min Chen, Hongming Liu, Yanling Zhou, Hailan Chen, Zhen Ma

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Benwei WangSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Dameng SunSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Sihan WangSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Min ChenSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Hongming LiuSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China. hongming9224@126.com.
Yanling ZhouSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Hailan ChenSchool of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China. hlchen319@163.com.
Zhen MaSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China. mzmz2009@sohu.com.
Guangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of Ni(II) sandwich-like coordinated compounds were synthesized by the reaction of nickel dichloride and ten 4'-(4-substituent phenyl)-2',2':6',2″-terpyridine ligands, and their structures were confirmed by elemental analysis, FT-IR, ESI-MS, solid state ultraviolet spectroscopy and X-ray single crystal diffraction analysis. Three human cancer cell lines and a normal human cell line were used for anti-proliferation potential study: human lung cancer cell line (A549), human esophageal cancer cell line (Eca-109), human liver cancer cells (Bel-7402) and normal human liver cells (HL-7702). The results show that these nickel complexes possess good inhibitory effects on the cancer cells, outperforming the commonly used clinical chemotherapy drug cisplatin. Especially, complexes 3 (-methoxyl) and 7 (-fluoro) have strong inhibitory ability against Eca-109 cell line with IC

Indexed as

Antineoplastic AgentsCoordination ComplexesDNAHumansLigandsMolecular Docking SimulationNickelSerum Albumin, BovineSpectroscopy, Fourier Transform InfraredAntineoplastic AgentsCoordination ComplexesDNALigandsNickelnickel chlorideSerum Albumin, BovineAnti-cancerMolecular dockingNickelTerpyridine

Identifiers

PMID37523103
OpenAlexW4385405906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.