Evidence map›Paper›PMID 37523018›Full record

ArticleEcoHealth2023

The Impact of Drought on HIV Care in Rural South Africa: An Interrupted Time Series Analysis.

Collins C Iwuji, Kathy Baisley, Molulaqhooa Linda Maoyi, Kingsley Orievulu, Lusanda Mazibuko, Sonja Ayeb-Karlsson, H Manisha Yapa, Willem Hanekom, Kobus Herbst, Dominic Kniveton

Erratum issuedAbstract read
In one paragraph

Article in EcoHealth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Collins C IwujiAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa. c.iwuji@bsms.ac.uk.
Kathy BaisleyAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Molulaqhooa Linda MaoyiDSI-MRC South African Population Research Infrastructure Network (SAPRIN), Johannesburg, South Africa.
Kingsley OrievuluAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Lusanda MazibukoAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Sonja Ayeb-KarlssonDepartment of Global Health & Infection, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PX, UK.
H Manisha YapaKirby Institute for Infection and Immunity, University of New South Wales Sydney, Sydney, Australia.
Willem HanekomAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Kobus HerbstAfrica Health Research Institute, Mtubatuba, KwaZulu-Natal, South Africa.
Dominic KnivetonSchool of Global Studies, University of Sussex, Brighton, UK.

Funding

Wellcome TrustWellcome Trust 201433/Z/16/A
6 · The paper itself

Abstract

This analysis investigates the relationship between drought and antiretroviral treatment (ART) adherence and retention in HIV care in the Hlabisa sub-district, KwaZulu-Natal, South Africa. Data on drought and ART adherence and retention were collated for the study period 2010-2019. Drought was quantified using the 3-month Standard Precipitation Evapotranspiration Index (SPEI) and Standard Precipitation Index (SPI) from station data. Adherence, proxied by the Medication Possession Ratio (MPR), and retention data were obtained from the public ART programme database. MPR and retention were calculated from individuals aged 15-59 years who initiated ART between January 2010 and December 2018 and visited clinic through February 2019. Between 01 January 2010 and 31 December 2018, 40,714 individuals started ART in the sub-district and made 1,022,760 ART visits. The SPI showed that 2014-2016 were dry years, with partial recovery after 2016 in the wet years. In the period from 2010 to 2012, mean 6-month MPR increased from 0.85 in July 2010 to a high of 0.92 in December 2012. MPR then decreased steadily through 2013 and 2014 to 0.78 by December 2014. The mean proportion retained in care 6 months after starting ART showed similar trends to MPR, increasing from 86.9% in July 2010 to 91.4% in December 2012. Retention then decreased through 2013, with evidence of a pronounced drop in January 2014 when the odds of retention decreased by 30% (OR = 0.70, CI = 0.53-0.92, P = 0.01) relative to the end of 2013. Adherence and retention in care decreased during the drought years.

Indexed as

Anti-HIV AgentsHIV InfectionsDroughtsHumansInterrupted Time Series AnalysisSouth AfricaAnti-HIV AgentsAdherenceDroughtHIVRetentionSouth AfricaSub-Saharan Africa

Identifiers

PMID37523018
PMCPMC10613144

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.