Evidence map›Paper›PMID 37521653›Full record

ArticleACS omega2023

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents.

Ezequiel F Bruna-Haupt, Marcelle D Perretti, Hugo A Garro, Romen Carrillo, Félix Machín, Isabel Lorenzo-Castrillejo, Lucas Gutiérrez, Esteban G Vega-Hissi, Macarena Mamberto, Mauricio Menacho-Marquez and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Ezequiel F Bruna-HauptDepartment of Chemistry, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis 5700, Argentina.ORCID https://orcid.org/0000-0003-2644-6935
Marcelle D PerrettiInstitute of Bio-Organics Antonio González, Department of Organic Chemistry, University of La Laguna, Institute of Natural Products and Agrobiology, IPNA-CSIC, La Laguna 38206, Spain.
Hugo A GarroDepartment of Chemistry, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis 5700, Argentina.
Romen CarrilloInstitute of Bio-Organics Antonio González, Department of Organic Chemistry, University of La Laguna, Institute of Natural Products and Agrobiology, IPNA-CSIC, La Laguna 38206, Spain.ORCID https://orcid.org/0000-0002-7078-300X
Félix MachínResearch Unit, Nuestra Señora de Candelaria University Hospital, Santa Cruz de Tenerife 38010, Spain, Institute of Biomedical Technologies, University of La Laguna, Tenerife 38200, Spain.
Isabel Lorenzo-CastrillejoResearch Unit, Nuestra Señora de Candelaria University Hospital, Santa Cruz de Tenerife 38010, Spain, Institute of Biomedical Technologies, University of La Laguna, Tenerife 38200, Spain.
Lucas GutiérrezDepartment of Chemistry, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis 5700, Argentina.
Esteban G Vega-HissiDepartment of Chemistry, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis 5700, Argentina.
Macarena MambertoNational University of Rosario, Rosario, Santa Fe 3100, Argentina.
Mauricio Menacho-MarquezNational University of Rosario, Rosario, Santa Fe 3100, Argentina.
Claudio O FernándezMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC), and Instituto de Investigaciones para el Descubrimiento de Fármacos de Rosario (IIDEFAR, UNR-CONICET), Rosario 2002, Argentina.
Celina GarcíaInstitute of Bio-Organics Antonio González, Department of Organic Chemistry, University of La Laguna, Institute of Natural Products and Agrobiology, IPNA-CSIC, La Laguna 38206, Spain.ORCID https://orcid.org/0000-0002-5049-9466
Carlos R PungitoreDepartment of Chemistry, Faculty of Chemistry, Biochemistry and Pharmacy, National University of San Luis, San Luis 5700, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad de La Laguna · ESNational University of San Luis · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A library of structurally related coumarins was generated through synthesis reactions and chemical modification reactions to obtain derivatives with antiproliferative activity both

Identifiers

PMID37521653
PMCPMC10373209
OpenAlexW4384155824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.