Evidence map›Paper›PMID 37521107›Full record

ReviewDrugs in context2023

The treatment of mild upper respiratory tract infections - a position paper with recommendations for best practice.

Andrew Smith, Peter Kardos, Oliver Pfaar, Winfried Randerath, Guillermo Estrada Riolobos, Fulvio Braido, Laura Sadofsky

Open access · goldAbstract readReview
In one paragraph

Review in Drugs in context, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Andrew SmithSchool of Psychology, Cardiff University, Cardiff, UK.
Peter KardosCentre of Allergy, Respiratory and Sleep Medicine, Maingau Clinic of the Red Cross, Frankfurt am Main, Germany.
Oliver PfaarDepartment of Otorhinolaryngology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Winfried RanderathInstitute of Pneumology, University of Cologne, Cologne, Germany.
Guillermo Estrada RiolobosSpanish Society Clinical Family and Community Pharmacy (SEFAC), Paseo de las Delicias, Madrid, Spain.
Fulvio BraidoIstituti di Ricovero e Cura a Carattere Scientifico, Ospedale Policlinico San Martino, Genova, Italy.
Laura SadofskyHull York Medical School, University of Hull, Hull, UK.
Cardiff University · GBGerman Red Cross · DEKrankenhaus Bethanien · DEPhilipps University of Marburg · DESpanish Society of Family and Community Medicine · ESUniversity of Genoa · ITUniversity of Hull · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the waning severity of COVID-19 due to vaccination and the development of immunity, the current variants of SARS-CoV-2 often lead to mild upper respiratory tract infections (MURTIs), suggesting it is an appropriate time to review the pathogenesis and treatment of such illnesses. The present article reviews the diverse causes of MURTIs and the mechanisms leading to symptomatic illness. Different symptoms of MURTIs develop in a staggered manner and require targeted symptomatic treatment. A wide variety of remedies for home treatment is available, including over-the-counter drugs and plant-derived substances. Recent pharmacological research has increased the understanding of molecular effects, and clinical studies have shown the efficacy of certain herbal remedies. However, the use of subjective endpoints in these clinical studies may suggest limited validity of the results. In this position paper, the importance of patient-centric outcomes, including a subjective perception of improved well-being, is emphasized. A best practice approach for the management of MURTIs, in which pharmacists and physicians create an improved multi-professional healthcare setting and provide healthcare education to patients, is proposed. Pharmacists act as first-line consultants and provide patients with remedies, considering the individual patient's preferences towards chemical or plant-derived drugs and providing advice for self-monitoring. Physicians act as second-line consultants if symptoms worsen and subsequently initiate appropriate therapies. In conclusion, general awareness of MURTIs should be increased amongst medical professionals and patients, thus improving their management.

Indexed as

common coldcoronaviruscoughCOVID-19 pandemicholistic healthmild upper respiratory tract infectionspharmacistrhinitisrhinovirussleep

Identifiers

PMID37521107
PMCPMC10379023
OpenAlexW4385219193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.