Evidence map›Paper›PMID 37520603›Full record

ArticleThe Saudi dental journal2023

Cloning, purification and characterization of human dentine matrix protein 1(DMP1).

Tarek El-Bialy, Dror Aizenbud, Hamid Sadeghi, Paul Scott, Itay Aizenbud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Saudi dental journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tarek El-BialyDivision Orthodontics, School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Dror AizenbudDepartment of Orthodontics and Craniofacial Anomalies, School of Graduate Dentistry, Rambam Health Care Center and Technion Haifa, Israel.
Hamid SadeghiDepartment of Dentistry, University of Alberta, Edmonton, Canada.
Paul ScottDepartment of Biochemistry, University of Alberta, Edmonton Canada.
Itay AizenbudInstitute of Dental Sciences, Faculty of Dental Medicine, Hebrew University, Jerusalem; Medical Corps, Israel Defense Forces, Tel-Hashomer, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Human teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human DMP1. Materials and methods: The DMP1 gene sequence was prepared and cloned by transfection of human 293 cells. Results: The recombinant DMP1 was purified and characterized. Conclusion: The results suggested its future use in dental tissue regeneration and tissue engineering.

Indexed as

CloningDentine matrix proteinHumanPurification

Identifiers

PMID37520603
PMCPMC10373089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.