Evidence map›Paper›PMID 37520600›Full record

ReviewThe Saudi dental journal2023

Peri-implantitis and systemic inflammation: A critical update.

Nasser M Assery, Carlos A Jurado, Mansour K Assery, Kelvin I Afrashtehfar

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Saudi dental journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Peri-implantitis: a systemic burden for our patients.Frontiers in dental medicine · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. International journal of molecular and cellular medicine · 2025
    Review
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  16. Review
  17. Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Nasser M AsseryDepartment of Periodontology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY 14642, USA.
Carlos A JuradoDepartment of Prosthodontics, School of Dentistry, Iowa University, Iowa City, IA 52242, USA.
Mansour K AsseryCollege of Dentistry, Riyadh Elm University, Riyadh 13244, Saudi Arabia.
Kelvin I AfrashtehfarEvidence-Based Practice Unit (EBPU), Clinical Sciences Department, College of Dentistry, Ajman University, PO Box 346, Ajman City, AE, United Arab Emirates.
Eastman Chemical Company (United States) · USRiyadh Elm University · SAUniversity of Bern · CHUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, including uncontrolled diabetes mellitus, psychological stress, cardiovascular disease, obesity, and infectious diseases such as COVID-19. As an inflammatory disease, peri-implantitis may trigger systemic inflammation by elevating circulating levels of pro-inflammatory cytokines, which could have unknown impacts on overall health. While the relationship between periodontal health and systemic conditions is better understood, the association between peri-implant disease and systemic inflammation remains unclear. Therefore, this comprehensive review aims to summarize the most recent evidence on the relationship between peri-implantitis and systemic inflammation, focusing on biological complications, microbiology, and biomarkers. This review aims to enhance our understanding of the links between peri-implantitis and systemic inflammation and promote further research in this field by discussing the latest insights and clinical implications.

Indexed as

Biological complicationsBiomarkersCardiovascular diseaseDental implantsInflammationMicrobiologyPeri-implantitisSystemic disease

Identifiers

PMID37520600
PMCPMC10373087
OpenAlexW4375845057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.