Evidence map›Paper›PMID 37520545›Full record

ArticleFrontiers in immunology2023

The methylation profile of

Marta Gorzkiewicz, Ewa Łoś-Rycharska, Julia Gawryjołek, Marcin Gołębiewski, Aneta Krogulska, Tomasz Grzybowski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marta GorzkiewiczDepartment of Forensic Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Ewa Łoś-RycharskaDepartment of Pediatrics, Allergology and Gastroenterology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Julia GawryjołekDepartment of Pediatrics, Allergology and Gastroenterology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Marcin GołębiewskiDepartment of Plant Physiology and Biotechnology, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Aneta KrogulskaDepartment of Pediatrics, Allergology and Gastroenterology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Tomasz GrzybowskiDepartment of Forensic Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland.
Nicolaus Copernicus University · PLCollegium Medicum in Bydgoszcz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Epigenetic dynamics has been indicated to play a role in allergy development. The environmental stimuli have been shown to influence the methylation processes. This study investigated the differences in CpGs methylation rate of immune-attached genes between healthy and allergic infants. The research was aimed at finding evidence for the impact of environmental factors on methylation-based regulation of immunological processes in early childhood. Methods: The analysis of methylation level of CpGs in the Results: The significantly lower methylation level of Conclusion: The

Indexed as

Dermatitis, AtopicDNA MethylationEnvironmental ExposureFood HypersensitivityForkhead Transcription FactorsCpG IslandsEpigenesis, GeneticFemaleHumansInfantInfant, NewbornInterferon-gammaInterleukin-10Interleukin-4Interleukin-5MaleForkhead Transcription FactorsFOXP3 protein, humanIFNG protein, humanIL10 protein, humanIL4 protein, humanIL5 protein, humanInterferon-gammaInterleukin-10Interleukin-4Interleukin-5allergyDNA methylationenvironmental exposureFOXP3IFNGIL10IL4IL5

Identifiers

PMID37520545
PMCPMC10373304
OpenAlexW4384199157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.