ArticleFrontiers in aging neuroscience2023
Dementia incidence and population-attributable fraction for dementia risk factors in Republic of Korea: a 12-year longitudinal follow-up study of a national cohort.
Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Population attributable fractions of a wide range of peripheral diseases for the burden of dementia.Nature human behaviour · 2026Pooled it
- Pooled it
- The immuno-neurological axis: association between autoimmune diseases and dementia risk.GeroScience · 2026Article
- National Surveillance-Based Retrospective Longitudinal Analysis of Dementia Prevalence Trends in the Republic of Korea, 2016-2025, with a One-Year 2026 Forecast Using National Health Insurance Service Administrative Data.Journal of clinical medicine · 2026Article
- The incidence of dementia in populations around the globe.Current opinion in psychiatry · 2026Review
- Sleep disorders and sleep behaviors as predictors of neurodegenerative diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Comparative risk of dementia between direct oral anticoagulants and warfarin after atrial fibrillation related ischemic stroke.Frontiers in aging neuroscience · 2026Article
- Systemic proteomic and organ aging signatures associated with plasma Aβ oligomerization in a Korean cohort: a cross-sectional study.Frontiers in aging neuroscience · 2026Article
- Effects of a 12-Week Hybrid Analog-Digital Cognitive Training on Cognitively Unimpaired Older Adults: A Pilot Single-Blind Randomized Controlled Trial.Dementia and neurocognitive disorders · 2025Article
- Trajectories of Alzheimer's Disease Prevalence among National Health Insurance and Medical Aid Beneficiaries from 2010 to 2019.Yonsei medical journal · 2025Article
- Impact of smoking, diabetes, and exercise on dementia risk in women with osteoporosis: a nationwide cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Association between sacubitril/valsartan and risk of dementia in patients with heart failure: a nationwide cohort study.European heart journal. Cardiovascular pharmacotherapy · 2025Article
- Effect of Social Activity on All-Cause Dementia Among South Korean Elders: A Retrospective Cohort Study.Health science reports · 2025Article
- Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database.The journal of prevention of Alzheimer's disease · 2025Article
- Effects of risk factors on the development and mortality of early- and late-onset dementia: an 11-year longitudinal nationwide population-based cohort study in South Korea.Alzheimer's research & therapy · 2024Article
- Impact of the COVID-19 pandemic on mortality and loss to follow-up among patients with dementia receiving anti-dementia medications.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We aimed to investigate the incidence of dementia by age and year as well as the population-attributable fractions (PAFs) for known dementia risk factors in Republic of Korea. Methods: A 12-year, nationwide, population-based, retrospective cohort study was conducted. We used customized health information from the National Health Insurance Service (NHIS) data from 2002 to 2017. We analyzed age- and sex-adjusted incidence rates and PAF of dementia for each risk factor such as depression, diabetes, hemorrhagic stroke, ischemic stroke, hypertension, osteoporosis and physical inactivity using Levin's formula. Results: Of the 794,448 subjects in the dementia-free cohort, 49,524 (6.2%) developed dementia. Dementia incidence showed annual growth from 1.56 per 1,000 person-years in 2006 to 6.94 per 1,000 person-years in 2017. Of all dementia cases, 34,544 subjects (69.8%) were female and 2,479 subjects (5.0%) were early onset dementia. AD dementia accounted for 66.5% of the total dementia incidence. Considering relative risk and prevalence, physical inactivity attributed the greatest to dementia (PAF, 8.1%), followed by diabetes (PAF, 4.2%), and hypertension (PAF, 2.9%). Altogether, the significant risk factors increased the risk of dementia by 18.0% (overall PAF). Conclusion: We provided the incidence of dementia and PAFs for dementia risk factors in Republic of Korea using a 12-year, nationwide cohort. Encouraging lifestyle modifications and more aggressive control of risk factors may effectively prevent dementia.
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