Evidence map›Paper›PMID 37519905›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

The Independent Effects of Kidney Length and Vascular Plaque on Ten-Year Outcomes of Extended Criteria Donor Kidney Transplants.

Bekir Tanriover, Darren Stewart, Layla Kamal, Muhammad Saeed, Matthew Cooper, Julia Foutz, Harrison McGehee, Gaurav Gupta

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Bekir TanrioverDivision of Nephrology, University of Arizona, Tucson, AZ, United States.
Darren StewartDepartment of Surgery, New York University Langone Health, New York City, NY, United States.
Layla KamalDivision of Nephrology, Virginia Commonwealth University, Richmond, VA, United States.
Muhammad SaeedDivision of Nephrology, Virginia Commonwealth University, Richmond, VA, United States.
Matthew CooperMedical College of Wisconsin, Milwaukee, WI, United States.
Julia FoutzUnited Network for Organ Sharing, Richmond, VA, United States.
Harrison McGeheeUnited Network for Organ Sharing, Richmond, VA, United States.
Gaurav GuptaDivision of Nephrology, Virginia Commonwealth University, Richmond, VA, United States.
Virginia Commonwealth University · USDivision of Chemistry · USMedical College of Wisconsin · USNYU Langone Health · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The independent effects of deceased donor kidney length and vascular plaque on long-term graft survival are not established. Utilizing DonorNet attachments from 4,480 expanded criteria donors (ECD) recovered between 2008 and 2012 in the United States with at least one kidney biopsied and transplanted, we analyzed the relationship between kidney length and vascular plaques and 10-year hazard of all-cause graft failure (ACGF) using causal inference methods in a Cox regression framework. The composite plaque score (range 0-4) and the presence of any plaque (yes, no) was also analyzed. Kidney length was modeled both categorically (<10, 10-12, >12 cm) as well as numerically, using a restricted cubic spline to capture nonlinearity. Effects of a novel composite plaque score 4 vs. 0 (HR 1.08; 95% CI: 0.96, 1.23) and the presence of any vascular plaque (HR 1.08; 95% CI: 0.98, 1.20) were attenuated after adjustment. Likewise, we identified a potential nonlinear relationship between kidney length and the 10-year hazard of ACGF, however the strength of the relationship was attenuated after adjusting for other donor factors. The independent effects of vascular plaque and kidney length on long-term ECD graft survival were found to be minimal and should not play a significant role in utilization.

Indexed as

Kidney TransplantationGraft SurvivalHumansKidneyRetrospective StudiesTissue DonorsTreatment OutcomeUnited Statesdeceased donorexpanded criteria donorkidney anatomylengthvascular plaque

Identifiers

PMID37519905
PMCPMC10379651
OpenAlexW4384298066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.