Evidence map›Paper›PMID 37519629›Full record

ArticleNAR cancer2023

CDK2 regulates collapsed replication fork repair in CCNE1-amplified ovarian cancer cells via homologous recombination.

Victoria E Brown, Sydney L Moore, Maxine Chen, Nealia House, Philip Ramsden, Hsin-Jung Wu, Scott Ribich, Alexandra R Grassian, Yoon Jong Choi

Open access · goldAbstract read
In one paragraph

Article in NAR cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Phlorotannins fromMarine drugs · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Myt1 Kinase: An Emerging Cell-Cycle Regulator for Cancer Therapeutics.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Review
  16. Targeting CDK2 to combat drug resistance in cancer therapy.Future oncology (London, England) · 2024
    Review
  17. Article
  18. Cancer takes many paths through G1/S.Trends in cell biology · 2024
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Victoria E BrownBlueprint Medicines, Cambridge, MA 02139, USA.ORCID 0009-0005-1586-8392
Sydney L MooreBlueprint Medicines, Cambridge, MA 02139, USA.
Maxine ChenBlueprint Medicines, Cambridge, MA 02139, USA.
Nealia HouseBlueprint Medicines, Cambridge, MA 02139, USA.ORCID 0000-0003-1264-7699
Philip RamsdenBlueprint Medicines, Cambridge, MA 02139, USA.
Hsin-Jung WuBlueprint Medicines, Cambridge, MA 02139, USA.
Scott RibichBlueprint Medicines, Cambridge, MA 02139, USA.
Alexandra R GrassianBlueprint Medicines, Cambridge, MA 02139, USA.
Yoon Jong ChoiBlueprint Medicines, Cambridge, MA 02139, USA.
Blueprint Medicines (United States) · USTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cyclin-Dependent Kinase 2Cyclin ECystadenocarcinoma, SerousDNA RepairDNA ReplicationHomologous RecombinationOncogene ProteinsOvarian NeoplasmsAnimalsCell Line, TumorDNA DamageFemaleGene AmplificationHumansMiceXenograft Model Antitumor AssaysCCNE1 protein, humanCDK2 protein, humanCyclin-Dependent Kinase 2Cyclin EOncogene Proteins

Identifiers

PMID37519629
PMCPMC10373114
OpenAlexW4385368280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.