ArticleBiological psychiatry global open science2023
Atypical Functional Network Properties and Associated Dimensions of Child Psychopathology During Rest and Task Performance.
Article in Biological psychiatry global open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- The topology of adolescent mental health.medRxiv : the preprint server for health sciences · 2026Article
- Causal Effects of Enhanced Parenting on Resting-State Graph Properties of Adolescents at Risk for Maltreatment.Biological psychiatry global open science · 2026Article
- Perinatal insult dimensions and developmental trajectories of psychotic-like experiences.Schizophrenia (Heidelberg, Germany) · 2025Article
- Longitudinal associations between youth prosocial behavior and dimensions of psychopathology.JCPP advances · 2025Article
- Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population.Molecular psychiatry · 2025Article
- Gray matter volume associations in youth with ADHD features of inattention and hyperactivity/impulsivity.Human brain mapping · 2024Article
- Cognitive and Psychiatric Relevance of Dynamic Functional Connectivity States in a Large (N>10,000) Children Population.Research square · 2024Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
Background: When brain networks deviate from typical development, this is thought to contribute to varying forms of psychopathology. However, research has been limited by the reliance on discrete diagnostic categories that overlook the potential for psychological comorbidity and the dimensional nature of symptoms. Methods: This study examined the topology of functional networks in association with 4 bifactor-defined psychopathology dimensions-general psychopathology, internalizing symptoms, conduct problems, and attention-deficit/hyperactivity disorder symptoms-via the Child Behavior Checklist in a sample of 3568 children from the ABCD (Adolescent Brain Cognitive Development) Study. Local and global graph theory metrics were calculated at rest and during tasks of reward processing, inhibition, and working memory. Results: Greater attention-deficit/hyperactivity disorder symptoms were associated with reduced modularity across rest and tasks as well as reduced local efficiency in motor networks at rest. Results survived sensitivity analyses for medication and socioeconomic status. Greater conduct problem symptoms were associated with reduced modularity on working memory and reward processing tasks; however, these results did not persist after sensitivity analyses. General psychopathology and internalizing symptoms showed no significant network associations. Conclusions: Our findings suggest reduced efficiency in topology in those with greater attention-deficit/hyperactivity disorder symptoms across 4 critical cognitive states, with conduct problems also showing network deficits, although less consistently. This may suggest that modularity deficits are a neurobiological marker of externalizing behavior in children. Such specificity has not been demonstrated before using graph theory metrics and has the potential to redefine our understanding of network deficits in children with psychopathology symptoms.
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