Evidence map›Paper›PMID 37519413›Full record

ArticleWellcome open research2021

Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial.

Peter Olupot-Olupot, William Okiror, Hellen Mnjalla, Rita Muhindo, Sophie Uyoga, Ayub Mpoya, Thomas N Williams, Rob terHeine, David M Burger, Britta Urban and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Peter Olupot-OlupotMbale Clinical Research Institute, Pallisa Road, PO Box 291, Mbale, Uganda.ORCID https://orcid.org/0000-0002-5757-609X
William OkirorMbale Clinical Research Institute, Pallisa Road, PO Box 291, Mbale, Uganda.
Hellen MnjallaKEMRI Wellcome Trust Research Programme, PO Box 230, Kilifi, Kenya.
Rita MuhindoMbale Clinical Research Institute, Pallisa Road, PO Box 291, Mbale, Uganda.ORCID https://orcid.org/0000-0003-4252-5924
Sophie UyogaKEMRI Wellcome Trust Research Programme, PO Box 230, Kilifi, Kenya.ORCID https://orcid.org/0000-0003-1746-7873
Ayub MpoyaKEMRI Wellcome Trust Research Programme, PO Box 230, Kilifi, Kenya.
Thomas N WilliamsKEMRI Wellcome Trust Research Programme, PO Box 230, Kilifi, Kenya.ORCID https://orcid.org/0000-0003-4456-2382
Rob terHeineDepartment of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
David M BurgerDepartment of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Britta UrbanLiverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
Roisin ConnonMRC Clinical Trials Unit, University College London, Aviation House, 125 Kingsway, London, WC28 6NH, UK.ORCID https://orcid.org/0000-0002-4408-4336
Elizabeth C GeorgeMRC Clinical Trials Unit, University College London, Aviation House, 125 Kingsway, London, WC28 6NH, UK.
Diana M GibbMRC Clinical Trials Unit, University College London, Aviation House, 125 Kingsway, London, WC28 6NH, UK.
A Sarah WalkerMRC Clinical Trials Unit, University College London, Aviation House, 125 Kingsway, London, WC28 6NH, UK.
Kathryn MaitlandKEMRI Wellcome Trust Research Programme, PO Box 230, Kilifi, Kenya.ORCID https://orcid.org/0000-0002-0007-0645
Kenya Medical Research Institute · KEMRC Clinical Trials Unit at UCL · GBMbale Hospital · UGRadboud University Nijmegen · NLLiverpool School of Tropical Medicine · GB

Funding

Medical Research Council MC_UU_00004/05Wellcome Trust 202800/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

African ChildrenAntibioticsazithromycinBacterial infectionBiomarkersClinical TrialPharmacodynamicsPharmacokineticsSevere Malaria

Identifiers

PMID37519413
PMCPMC10382785
OpenAlexW4315433627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.