Evidence map›Paper›PMID 37519344›Full record

ArticleCerebral circulation - cognition and behavior2023

Visualization of atrophy of medial temporal lobes and the septal nuclei in patients with transient ischaemic attack and controls.

Morgan J Schaeffer, Noaah Reaume, Meng Wang, Arooj Aftab, Alexander Pan, Sana Tariq, Meaghan Reid, Eric E Smith, Chris D'Esterre, Philip A Barber

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cerebral circulation - cognition and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Morgan J SchaefferDepartment of Psychology, University of Victoria, Victoria, British Columbia, Canada.
Noaah ReaumeDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
Meng WangDepartment of Community Health Sciences, University of Calgary, 3280 Hospital Drive NW Alberta, Calgary, Canada.
Arooj AftabDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
Alexander PanDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
Sana TariqCalgary Stroke Program, Department of Clinical Neurosciences, Foothills Medical Centre, 1403 - 29 Street NW, Calgary, Alberta, Canada.
Meaghan ReidCalgary Stroke Program, Department of Clinical Neurosciences, Foothills Medical Centre, 1403 - 29 Street NW, Calgary, Alberta, Canada.
Eric E SmithDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
Chris D'EsterreDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
Philip A BarberDepartment of Clinical Neurosciences, University of Calgary, 1403 29th Street NW, Calgary, Alberta, Canada.
University of Calgary · CAFoothills Medical Centre · CAUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Transient ischaemic attack (TIA) is associated with increased risk of cognitive decline and dementia as early as one-year post-event. Regional brain atrophy measurements may predict future cognitive decline. Methods: Baseline demographic, vascular risk factors, structural imaging and cognitive tests scores were compared between 103 Patients with TIA and 103 age-and-sex-matched controls from the Predementia Neuroimaging of Transient Ischaemic Attack (PREVENT) Study. MTA was assessed using the Schelten's Scale, and ISD was calculated as the distance between the septal nucleus of each hemisphere. Multiple linear regression models were used to evaluate how MTA and ISD related to cognitive change after adjusting for covariates. Results: Patients with TIA had larger ISD measurements (1.4 mm [SD=1.2] vs. 0.9 mm [SD=1.0]); Conclusions: Patients with TIA had higher MTA scores and ISD measurements than controls, but neither were predictors of cognitive decline at one year. Future studies with longer follow-up periods will be required to determine whether higher MTA scores and ISD predict risk of cognitive decline in patients with TIA.

Indexed as

Cognitive assessmentInterseptal distanceMagnetic resonance imagingMedial temporal atrophyTransient ischemic attack

Identifiers

PMID37519344
PMCPMC10372167
OpenAlexW4383704034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.