Evidence map›Paper›PMID 37519232›Full record

ArticleAmerican journal of physiology. Cell physiology2023

Age-related decline in bone mineral transport and bone matrix proteins in osteoblasts from stromal stem cells.

Irina L Tourkova, Quitterie C Larrouture, Kelechi M Onwuka, Silvia Liu, Jianhua Luo, Paul H Schlesinger, Harry C Blair

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Irina L TourkovaResearch Service, VA Medical Center, Pittsburgh, Pennsylvania, United States.
Quitterie C LarroutureResearch Service, VA Medical Center, Pittsburgh, Pennsylvania, United States.
Kelechi M OnwukaResearch Service, VA Medical Center, Pittsburgh, Pennsylvania, United States.
Silvia LiuDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Jianhua LuoDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Paul H SchlesingerDepartment of Cell Biology & Physiology, Washington University in St. Louis, St. Louis, Missouri, United States.
Harry C BlairResearch Service, VA Medical Center, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-1152-3718
University of Pittsburgh · USWashington University in St. Louis · US

Funding

Epithelial Osteoblast Function: The Role of Acid TransportR01AR076146 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT, NELSON, DEBORAH J. · 2020 to 2024
$2.6M
Epithelial Osteoblast Function: The Role of Acid TransportR56AR076146 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT, NELSON, DEBORAH J. · 2019 to 2019
$652k
Regulation of Osteoblasts by ACTH and VEGFI01BX002490 · VA · VETERANS HEALTH ADMINISTRATION · PI BLAIR, HARRY COLBERT · 2015 to 2025
–
BLRD VA I01 BX002490NIAMS NIH HHS R01 AR076146NIAMS NIH HHS R56 AR076146
6 · The paper itself

Abstract

We studied osteoblast bone mineral transport and matrix proteins as a function of age. In isolated bone marrow cells from long bones of young (3 or 4 mo) and old (18 or 19 mo) mice, age correlated with reduced mRNA of mineral transport proteins: alkaline phosphatase (ALP), ankylosis (ANK), the Cl

Indexed as

Bone MatrixOsteoblastsAnimalsCarrier ProteinsCell DifferentiationCells, CulturedMiceMineralsRNA, MessengerStem CellsWnt Signaling PathwayX-Ray MicrotomographyCarrier ProteinsMineralsRNA, Messengeragingbone mineralizationosteoblastosteoporosisstromal stem cells

Identifiers

PMID37519232
PMCPMC10635645
OpenAlexW4385405862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.