Evidence map›Paper›PMID 37518906›Full record

ArticleJournal of applied gerontology : the official journal of the Southern Gerontological Society2023

Social Isolation and Loneliness in a Population Study of Cognitive Impairment: The MYHAT Study.

Fang Fang, Tiffany F Hughes, Andrea Weinstein, Hiroko H Dodge, Erin P Jacobsen, Chung-Chou H Chang, Beth E Snitz, Mary Ganguli

Abstract read
In one paragraph

Article in Journal of applied gerontology : the official journal of the Southern Gerontological Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Loneliness and Plasma Biomarkers of Neurodegeneration in Community-Dwelling Older Adults: Cross-Sectional and Longitudinal Analyses.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fang FangResearch and Infrastructure Research Service (RISE) and Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USA.ORCID 0000-0003-1961-7660
Tiffany F HughesDepartment of Graduate Studies in Health and Rehabilitation Sciences, Bitonte College of Health and Human Services, Youngstown State University, Youngstown, OH, USA.ORCID 0000-0002-3526-9005
Andrea WeinsteinDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Hiroko H DodgeDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Erin P JacobsenDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Chung-Chou H ChangDepartment of Medicine, and Department of Biostatistics, School of Medicine and School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Beth E SnitzDepartment of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Mary GanguliDepartments of Psychiatry, Neurology, and Epidemiology, School of Medicine and School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Mild Cognitive Impairment: A Prospective Community StudyR37AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carmen Andreescu, MARY GANGULI · 2021 to 2026
$18.2M
Intraindividual Cognitive Variability as an Early Marker of Alzheimer's DiseaseK23AG076663 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Andrea Weinstein · 2022 to 2026
$915k
NIA NIH HHS K23 AG076663NIA NIH HHS R37 AG023651
6 · The paper itself

Abstract

In this study, we examined associations of social isolation and loneliness with cognitive impairment among older adults from a Rust Belt region in Southwest Pennsylvania. We used data from the population-based Monongahela-Youghiogheny Healthy Aging Team (MYHAT) study. We found that (a) 11 items combined into two reliable composites of social isolation and loneliness; (b) unique to this study, providing unpaid help to others was an indicator of reduced social isolation; (c) social isolation and loneliness were positively associated with cognitive impairment; and (d) these associations were appreciably attenuated by general health and physical functional status and depressive symptoms, respectively. We concluded that social isolation and loneliness are differentially associated with older adults' cognitive health, and that their effects might operate through separate pathways. Approaches to address social isolation and loneliness should consider the community context and its implications for older adults' cognitive health.

Indexed as

Cognitive DysfunctionHealthy AgingAgedHumansLonelinessPennsylvaniaSocial Isolationcognitionhealthlonelinesssocial isolation

Identifiers

PMID37518906
PMCPMC10825064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.