Evidence map›Paper›PMID 37518896›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2024

Smaller Hippocampal Volume Is Associated With Reduced Posttraumatic Stress Symptoms in Children With Cancer and Survivors Following a Brief Novel Martial Arts-Based Intervention.

Julia M Evanski, Allesandra Iadipaolo, Samantha L Ely, Clara G Zundel, Leah C Gowatch, Amanpreet Bhogal, Zazai Owens, Cindy Cohen, Elimelech Goldberg, Martin H Bluth and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Julia M EvanskiDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Allesandra IadipaoloDepartment of Pharmacy Practice, Wayne State University, Detroit, MI 48201, USA.
Samantha L ElyDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Clara G ZundelDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Leah C GowatchDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Amanpreet BhogalDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Zazai OwensDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Cindy CohenKids Kicking Cancer, Southfield, MI, USA.
Elimelech GoldbergKids Kicking Cancer, Southfield, MI, USA.
Martin H BluthKids Kicking Cancer, Southfield, MI, USA.
Jeffrey TaubDepartment of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Felicity W K HarperDepartment of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Christine A RabinakDepartment of Pharmacy Practice, Wayne State University, Detroit, MI 48201, USA.
Hilary A MarusakDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.ORCID 0000-0002-0771-6795
Wayne State University · USMaimonides Medical Center · US

Funding

Endocannabinoids and the development of extinction recall neural circuitry in adolescentsK01MH119241 · NIMH · WAYNE STATE UNIVERSITY · PI MARUSAK, HILARY · 2019 to 2023
$842k
Effects of peer victimization on physiological markers of threat sensitivity in adolescentsR21HD105882 · NICHD · WAYNE STATE UNIVERSITY · PI MARUSAK, HILARY, SCHACTER, HANNAH L · 2022 to 2023
$424k
NICHD NIH HHS R21 HD105882NIMH NIH HHS K01 MH119241
6 · The paper itself

Abstract

purposeChildren with cancer and survivors frequently report posttraumatic stress symptoms (PTSS), which are associated with volumetric changes in stress-sensitive brain regions, including the hippocampus.

methodsWe examined the impact of a novel, 4-week martial-arts-based meditative intervention on cancer-related PTSS in 18 pediatric patients and survivors and whether baseline hippocampal volumes correlate with PTSS severity and/or PTSS changes over time.

resultsOverall, PTSS did not significantly change from baseline to post-intervention. Smaller hippocampal volume was correlated with more severe re-experiencing PTSS at baseline, and greater reductions in PTSS post-intervention.

conclusionsTogether, hippocampal volume may be a biomarker of PTSS severity and intervention response. Identifying hippocampal volume as a potential biomarker for PTSS severity and intervention response may allow for more informed psychosocial treatments.

Indexed as

Martial ArtsNeoplasmsStress Disorders, Post-TraumaticBiomarkersChildHippocampusHumansNeuropsychological TestsSurvivorsBiomarkersAdolescentsChildrenMindfulnessNeuroimagingPosttraumatic stress disorderPsycho-oncology

Identifiers

PMID37518896
PMCPMC11485273
OpenAlexW4385407014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.