Evidence map›Paper›PMID 37517673›Full record

ArticleToxicology letters2023

Early microRNA responses in rodent liver mediated by furan exposure establish dose thresholds for later adverse outcomes.

Gail M Nelson, Gleta K Carswell, Carol D Swartz, Leslie Recio, Carole L Yauk, Brian N Chorley

Open access · greenAbstract read
In one paragraph

Article in Toxicology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Gail M NelsonUS Environmental Protection Agency, Research Triangle Park, NC 27709, USA.
Gleta K CarswellUS Environmental Protection Agency, Research Triangle Park, NC 27709, USA.
Carol D SwartzInotiv Co., 601 Keystone Park Drive, Suite 200, Morrisville, NC 27560, USA.
Leslie RecioScitoVation, 100 Capitola Drive Suite 106, Durham, NC 27713, USA.
Carole L YaukDept. Of Biology, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
Brian N ChorleyUS Environmental Protection Agency, Research Triangle Park, NC 27709, USA. Electronic address: chorley.brian@epa.gov.
Research Triangle Park Foundation · USEnvironmental Protection Agency · USUniversity of Ottawa · CA

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

To reduce reliance on long-term in vivo studies, short-term data linking early molecular-based measurements to later adverse health effects is needed. Although transcriptional-based benchmark dose (BMD

Indexed as

MicroRNAsAnimalsFuransHepatocytesLiverMiceRodentiaFuransMicroRNAsBiomarkersFuranLiver injuryMicroRNAs

Identifiers

PMID37517673
PMCPMC10530563
OpenAlexW4385336550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.