Evidence map›Paper›PMID 37517262›Full record

ArticleDrug and alcohol dependence2023

Context and correlates of providing assistance with someone's first injection in the AIDS linked to the IntraVenous Experience cohort, Baltimore, MD.

Rachel E Gicquelais, Jacqueline Astemborski, Daniel Werb, Gregory D Kirk, Shruti H Mehta, Becky L Genberg

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rachel E GicquelaisUniversity of Wisconsin-Madison School of Nursing, 701 Highland AveMadisonWI53705, United States.
Jacqueline AstemborskiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe StBaltimoreMD21205, United States.
Daniel WerbCentre on Drug Policy Evaluation, Li Ka Shing Knowledge Institute, St. Michael's HospitalTorontoOntario, Canada; Department of Medicine, University of California San DiegoSan DiegoCA92161, United States.
Gregory D KirkDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe StBaltimoreMD21205, United States; Johns Hopkins University School of Medicine, Division of Infectious DiseasesBaltimoreMD21205, United States.
Shruti H MehtaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe StBaltimoreMD21205, United States.
Becky L GenbergDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe StBaltimoreMD21205, United States. Electronic address: bgenberg@jhu.edu.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
The AIDS Linked to the Intravenous Experience (ALIVE) StudyU01DA036297 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Gregory D Kirk, Shruti H Mehta · 2014 to 2026
$28.9M
Preventing HIV by modifying the context for injecting initiationDP2DA040256 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERB, DANIEL M · 2015 to 2015
$2.3M
NIAID NIH HHS P30 AI094189NIDA NIH HHS DP2 DA040256NIDA NIH HHS U01 DA036297
6 · The paper itself

Abstract

backgroundThe social processes around initiating injection may be well-suited to intervention, yet there is substantial heterogeneity in the reported experiences of people who inject drugs (PWID) who assist with another individual's first drug injection. We aimed to describe the lifetime prevalence and context of providing initiation assistance among a cohort of PWID.

methodsParticipants of the AIDS Linked to the IntraVenous Experience (ALIVE) cohort of PWID in Baltimore, Maryland (n=848) were surveyed during 2019-2020 about assisting with another person's first injection. Associations between factors related to injection risk and history of providing assistance were estimated using logistic regression models adjusted for sociodemographic and behavioral characteristics.

resultsAt baseline, participants were primarily male (66.1%), black (82.9%), aged a median of 42 years, and had been injecting a median of 18 years. Overall, 19% (n=157) of participants reported ever providing assistance for a median of 2 people (Interquartile Range: 1-4). Having hepatitis C infection (adjusted Odds Ratio [95% Confidence Interval]: 2.5 [1.4-4.6]), syringe sharing (2.2 [1.2-3.9]), and injecting ≥3 times per day (2.0 [1.2-3.4]) at study enrollment were associated with a history of assistance. Participants primarily assisted friends (58.0%), acquaintances (29.9%), and partners (21.7%). Common reasons for assisting were the other person's lack of injection knowledge (73.7%) or sharing drugs (44.9%). Additional reasons included to prevent injury.

conclusionPWID with a history of assisting with another person's first injection exhibited heightened vulnerability to infections and more frequent substance use. Expanding implementation of interventions with an emphasis on harm reduction is needed.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsSubstance Abuse, IntravenousAgedBaltimoreHumansMaleNeedle SharingSurveys and QuestionnairesHarm reductionInjection drug useInjection initiation assistancePeople who inject drugsSocial context

Identifiers

PMID37517262
PMCPMC10529208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.