Evidence map›Paper›PMID 37516933›Full record

ArticleAutophagy2023

AI-based AlphaFold2 significantly expands the structural space of the autophagy pathway.

Nidhi Malhotra, Shantanu Khatri, Ajit Kumar, Akanksha Arun, Purba Daripa, Saman Fatihi, Sureshkumar Venkadesan, Niyati Jain, Lipi Thukral

Abstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Autophagy3D: a comprehensive autophagy structure database.Database : the journal of biological databases and curation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nidhi MalhotraComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Shantanu KhatriComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Ajit KumarComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Akanksha ArunComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Purba DaripaComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Saman FatihiComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Sureshkumar VenkadesanNational Institute of Immunology, New Delhi, India.
Niyati JainComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Lipi ThukralComputational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.ORCID 0000-0002-1961-039X

Funding

DBT-Wellcome Trust India Alliance IA/I/21/2/505925Wellcome Trust
6 · The paper itself

Abstract

abbreviationsAF2: AlphaFold2; AF2-Mult: AlphaFold2 multimer; ATG: autophagy-related; CTD: C-terminal domain; ECTD: extreme C-terminal domain; FR: flexible region; MD: molecular dynamics; NTD: N-terminal domain; pLDDT: predicted local distance difference test; UBL: ubiquitin-like.

Indexed as

AutophagyUbiquitin-Conjugating EnzymesArtificial IntelligenceAutophagy-Related ProteinsFurylfuramideAutophagy-Related ProteinsFurylfuramideUbiquitin-Conjugating EnzymesAlphaFold2ATG7-ATG10 complexautophagic interactomeautophagymolecular dynamics simulations

Identifiers

PMID37516933
PMCPMC10621275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.