Evidence map›Paper›PMID 37516869›Full record

ArticleBMC women's health2023

Fertility specialists' views, behavior, and attitudes towards the use of endometrial scratching in Italy.

Stefano Palomba, Domenico Carone, Amerigo Vitagliano, Flavia Costanzi, Alice Fracassi, Tiziana Russo, Serena Del Negro, Altiero Biello, Aldo Di Filippo, Antonio Mangiacasale and 44 more

Open access · goldAbstract read
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Article in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors at 18 institutions in 1 country.

Stefano PalombaSant'Andrea Hospital, University "Sapienza" of Rome, Rome, Italy. prof.stefano.palomba@gmail.com.ORCID 0000-0003-2767-8295
Domenico CaroneEugin, Taranto, Italy.
Amerigo VitaglianoCentro Di PMA, Ospedale Di San Donà Di Piave, Venice, Italy.
Flavia CostanziSant'Andrea Hospital, University "Sapienza" of Rome, Rome, Italy.
Alice FracassiNike Medical Center, Rome, Italy.
Tiziana RussoGrande Ospedale Metropolitano, Reggio Calabria, Italy.
Serena Del NegroGatjc Fertility Center, Gioia Tauro, Reggio Calabria, Italy.
Altiero BielloASL Na2 Nord, Naples, Italy.
Aldo Di FilippoEugin, Taranto, Italy.
Antonio MangiacasaleCentro Di Riproduzione Assistita - CRA, Catania, Italy.
Antonio MonacoPromea, Turin, Italy.
Antonio RanieriClinica HERA, Giugliano in Campania, Naples, Italy.
Beatrice ErminiCentro Italiano Di Procreazione Assistita - CIPA, Rome, Italy.
Bruno Francesco BarbaCasa Di Cura "Salus", Brindisi, Italy.
Claudio CastelloCentro FIVET Città Di Torino, Casa Della Salute Valdese, Turin, Italy.
Federica Di GuardoAzienda Ospedaliero Universitaria Policlinico "G. Rodolico - San Marco", Catania, Italy.
Francesco Pastorella01 Procreazione: Centro Di Fecondazione Assistita, Mestre, Venice, Italy.
Elena BernasconiClinica San Carlo, Paderno Dugnano, Milan, Italy.
Ezio Michele TricaricoCentro Di PMA, Ospedale Di Nardò, Lecce, Italy.
Francesca FilippiFondazione IRCCS Ca' Grande - Ospedale Maggiore - University of Milan, Milan, Italy.
Francesco PolsinelliCentro STS, Sora, Frosinone, Italy.
Giuseppe Lo MonteCentro Di Medicina Della Riproduzione E Crioconservazione Dei Gameti, Ospedale Di Brunico, Bolzano, Italy.
Loredana M Sosa FernandezCentro Embryos, Battipaglia, Naples, Italy.
Marco GallettaCentro Di Procreazione Medicalmente Assistita, Azienda Ospedaliera "Papardo", Messina, Italy.
Paolo GiardinaIRCCS San Raffaele Hospital, Milan, Italy.
Pasquale TotaroCentro Di Procreazione Medicalmente Assistita, Ospedale Santa Maria, Bari, Italy.
Roberto LaganaraBiotech PMA, Padua, Italy.
Roberto LiguoriPoliambulatorio Vismed, Bari, Italy.
Matteo BuccheriGenersi Srl - Istituto Bernabeu Venecia, Venice, Italy.
Mario Montanino OlivaAltamedica, Rome, Italy.
Rosita PiscopoASL 5 Spezzino, La Spezia, Italy.
Assunta IulianoUOC Di Ostetricia E Ginecologia, Azienda Ospedaliera "San Carlo", Potenza, Italy.
Nicola InnantuoniCentro Chemis, Naples, Italy.
Irene RomanelloSSD Di Procreazione Medicalmente Assistita, Azienza Sanitaria Friuli Occidentale, Sacile, Pordenone, Italy.
Francesco SinatraAzienda ULSS 7 Pedemontana, Bassano del Grappa, Vicenza, Italy.
Annalisa LiprinoUnità Di Medicina Della Riproduzione - UMR, Catania, Italy.
Roberto ThiellaPoliambulatorio Teatro Nuovo, Vicenza, Italy.
Alessandra TiezziClinica Nuova Ricerca, Rimini, Italy.
Tiziana BartolottiCentro Demetra-Artebios, Lugo, Ravenna, Italy.
Alessandra TomasiOspedale San Luca, Trecenta, Rovigo, Italy.
Valeria FinocchiaroCentro Fertilia, Casa Di Cura "Falcidia", Catania, Italy.
Mario ThiellaPoliambulatorio Teatro Nuovo, Vicenza, Italy.
Giuseppa FuggettaSSD Di Procreazione Medicalmente Assistita, Azienza Sanitaria Friuli Occidentale, Sacile, Pordenone, Italy.
Sebastiano MessineoSant'Andrea Hospital, University "Sapienza" of Rome, Rome, Italy.
Francesco IsabellaClinical Institute of Sterility, Lamezia Terme, Catanzaro, Italy.
Marcello TripodiGrande Ospedale Metropolitano, Reggio Calabria, Italy.
Stefania IaccarinoCentro Chemis, Naples, Italy.
Giovanni Battista La SalaNetwork 9.Baby, Bologna, Italy.
Enrico PapaleoIRCCS San Raffaele Hospital, Milan, Italy.
Donatella CasertaSant'Andrea Hospital, University "Sapienza" of Rome, Rome, Italy.
Roberto MarciUniversity of Ferrara, Ferrara, Italy.
Edgardo SomiglianaFondazione IRCCS Ca' Grande - Ospedale Maggiore - University of Milan, Milan, Italy.
Antonino GuglielminoUnità Di Medicina Della Riproduzione - UMR, Catania, Italy.
Italian Society of Human Reproduction (SIRU)
Azienda Ospedaliera Sant'Andrea · ITCentro Medicina della Riproduzione · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale San Carlo · ITUniversity of Reggio Calabria · ITVita-Salute San Raffaele University · ITAccademia di Belle Arti di Frosinone · ITAzienda Ospedaliera Ospedali Riuniti Papardo Piemonte · ITCasa di Cura Città di Roma · ITCasa di Cura Columbus · ITFondazione Poliambulanza Istituto Ospedaliero · ITOspedale di San Donà di Piave · ITOspedale San Bassiano · ITOspedale Santa Maria · ITPoliclinico Universitario di Catania · ITPresidio Ospedaliero · ITSanta Maria Nuova Hospital · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometrial scratching (ES) or injury is intentional damage to the endometrium performed to improve reproductive outcomes for infertile women desiring pregnancy. Moreover, recent systematic reviews with meta-analyses and randomized controlled trials demonstrated that ES is not effective, data on the safety are limited, and it should not be recommended in clinical practice. The aim of the current study was to assess the view and behavior towards ES among fertility specialists throughout infertility centers in Italy, and the relationship between these views and the attitudes towards the use of ES as an add-on in their commercial setting.

methodsOnline survey among infertility centers, affiliated to Italian Society of Human Reproduction (SIRU), was performed using a detailed questionnaire including 45 questions with the possibility to give "closed" multi-choice answers for 41 items and "open" answers for 4 items. Online data from the websites of the infertility centers resulting in affiliation with the specialists were also recorded and analyzed. The quality of information about ES given on infertility centers websites was assessed using a scoring matrix including 10 specific questions (scored from 0 to 2 points), and the possible scores ranged from 0 to 13 points ('excellent' if the score was 9 points or more, 'moderate' if the score was between 5 and 8, and 'poor' if it was 4 points or less).

resultsThe response rate was of 60.6% (43 questionnaires / 71 infertility SIRU-affiliated centers). All included questionnaires were completed in their entirety. Most physicians (~ 70%) reported to offer ES to less than 10% of their patients. The procedure is mainly performed in the secretory phase (69.2%) using pipelle (61.5%), and usually in medical ambulatory (56.4%) before IVF cycles to improve implantation (71.8%) without drugs administration (e.g., pain drugs, antibiotics, anti-hemorrhagics, or others) before (76.8%) or after (64.1%) the procedure. Only a little proportion of infertility centers included in the analysis proposes formally the ES as an add-on procedure (9.3%), even if, when proposed, the full description of the indications, efficacy, safety, and costs is never addressed. However, the overall information quality of the websites was generally "poor" ranging from 3 to 8 and having a low total score (4.7 ± 1.6; mean ± standard deviation).

conclusionsIn Italy, ES is a procedure still performed among fertility specialists for improving the implantation rate in IVF patients. Moreover, they have a poor attitude in proposing ES as an add-on in the commercial setting.

Indexed as

Infertility, FemaleAttitudeEndometriumFemaleFertilityHumansItalyPregnancyEndometrial injuryEndometrial scratchingInfertilityIVFSterility

Identifiers

PMID37516869
PMCPMC10386779
OpenAlexW4385381787

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