Evidence map›Paper›PMID 37516762›Full record

ArticleNature communications2023

Combining amino acid PET and MRI imaging increases accuracy to define malignant areas in adult glioma.

Maciej Harat, Józefina Rakowska, Marek Harat, Tadeusz Szylberg, Jacek Furtak, Izabela Miechowicz, Bogdan Małkowski

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06466031 narecruitingnot on this mapstarted 2025, after this paper: background citation

Application of FET-PET in Fusion With MRI in the Surgical Treatment and Postoperative Radiotherapy of Glioblastoma Multiforme - a Randomized, Blinded, Prospective Study

TypeinterventionalSponsorCopernicus Memorial HospitalRan2025 to 2032Enrolled189ConditionsGlioblastoma MultiformeArmsMRI & PET fusion, MRI+T1C
NCT07668869 narecruitingnot on this mapstarted 2025, after this paper: background citation

Tumor Treating Fields (TTFields) Concomitant With Stereotactic Radiosurgery Based on FET-PET vs TTFields Alone for the Treatment of Recurrent, Glioblastoma (Tarrget 2.0)

TypeinterventionalSponsorProf. Franciszek Lukaszczyk Memorial Oncology CenterRan2025 to 2032Enrolled92ConditionsGlioblastoma, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Glioblastoma Multiforme, AdultArmsTumor Treating Fields (TTFields), FET-PET-Guided Stereotactic Radiosurgery
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 52 citations in OpenAlex.

  1. Annals of nuclear medicine · 2025
    Trial
  2. FET-PETTranslational cancer research · 2026
    Article
  3. Article
  4. Characteristics of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. Clinical potential of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Article
  8. Prognostic value of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  9. Comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Recent developments in translational imaging of in vivo gene therapy outcomes.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  17. A hybrid [European journal of nuclear medicine and molecular imaging · 2025
    Observational
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Maciej HaratDepartment of Neurooncology and Radiosurgery, Franciszek Lukaszczyk Oncology Center, Bydgoszcz, Poland. haratm@co.bydgoszcz.pl.ORCID 0000-0003-1785-3184
Józefina RakowskaDepartment of Neurosurgery, 10th Military Research Hospital, Bydgoszcz, Poland.
Marek HaratDepartment of Neurosurgery, 10th Military Research Hospital, Bydgoszcz, Poland.
Tadeusz SzylbergDepartment of Pathomorphology, 10th Military Research Hospital, Bydgoszcz, Poland.
Jacek FurtakDepartment of Neurosurgery, 10th Military Research Hospital, Bydgoszcz, Poland.
Izabela MiechowiczDepartment of Computer Science and Statistics, University of Medical Sciences, Poznan, Poland.ORCID 0000-0003-0751-4867
Bogdan MałkowskiDepartment of Nuclear Medicine, Franciszek Lukaszczyk Oncology Center, Bydgoszcz, Poland. malkowskib@co.bydgoszcz.pl.ORCID 0000-0003-1421-4694
Bydgoszcz University of Science and Technology · PLUniversity of Bydgoszcz · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate determination of the extent and grade of adult-type diffuse gliomas is critical to patient management. In clinical practice, contrast-enhancing areas of diffuse gliomas in magnetic resonance imaging (MRI) sequences are usually used to target biopsy, surgery, and radiation therapy, but there can be discrepancies between these areas and the actual tumor extent. Here we show that adding

Indexed as

Amino AcidsGliomaAdultBiological TransportHumansMagnetic Resonance ImagingPositron-Emission TomographyAmino Acids

Identifiers

PMID37516762
PMCPMC10387066
OpenAlexW4385380059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.