Evidence map›Paper›PMID 37516716›Full record

ReviewOphthalmology and therapy2023

Allogenic Lenticular Implantation for Correction of Refractive Error and Ectasia: Narrative Review.

Majid Moshirfar, Isabella M Stoakes, Elayna G Bruce, Amir Ali, Carter J Payne, David Furhiman, Yasmyne C Ronquillo, Phillip C Hoopes

Abstract readReview
In one paragraph

Review in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Ex Vivo Assessment of Excimer Laser-Assisted Lenticule Customization.Translational vision science & technology · 2026
    Article
  3. Article
  4. Nicotinamide mononucleotide, a potential future treatment in ocular diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Majid MoshirfarHDR Research Center, Hoopes Vision, Draper, UT, USA. cornea2020@me.com.ORCID http://orcid.org/0000-0003-1024-6250
Isabella M StoakesHDR Research Center, Hoopes Vision, Draper, UT, USA.
Elayna G BruceMcGovern Medical School, Houston, TX, USA.
Amir AliUniversity of Texas Medical Branch at Galveston, Galveston, TX, USA.
Carter J PayneHDR Research Center, Hoopes Vision, Draper, UT, USA.
David FurhimanMcGovern Medical School, Houston, TX, USA.
Yasmyne C RonquilloHDR Research Center, Hoopes Vision, Draper, UT, USA.
Phillip C HoopesHDR Research Center, Hoopes Vision, Draper, UT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntrastromal lenticule implantation is a promising treatment option for corneal pathologies, from refractive error to ectasia. In this narrative review, we intend to feature up-to-date literature supporting the use of lenticular tissue, a compelling method that can be customized for a variety of applications, providing an additional source of donor tissue for treating corneal diseases.

methodsWe searched databases PubMed, Mendeley, and Scopus last accessed 10 May 2023, for literature on stromal lenticules and narrowed based on relevance. Review articles, animal studies, ex vivo studies, and book chapters were excluded, while assessable and relevant articles published in English were included.

resultsStorage methods from using fresh lenticules to dehydration have proven successful, with cryopreservation maintaining structure and cellular viability for up to 10 years. Successful use of lenticules for treatment of numerous pathologies including corneal ectasias, hyperopia, and presbyopia with additional insight into the treatment of corneal ulcers and perforations are highlighted in this narrative review.

conclusionLenticular implantation is an innovative and advantageous treatment for various ocular pathologies, offering increased bioavailability, flexibility, and customization for patients. They can treat previously untreatable diseases and serve as a replacement for synthetic implants, with promising outcomes worldwide. Lenticular implantation has the potential to become a leading approach in ophthalmologic surgery. Further studies should aim to provide evidentiary support for a standardization of lenticule banking.

Indexed as

ALKAllogenic lenticule implantationCAIRSCorneal storage mediumHyperopiaIntrastromal keratoplastyNecklace lenticulePEARLPresbyopiaSMILE

Identifiers

PMID37516716
PMCPMC10442033

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.