Evidence map›Paper›PMID 37516422›Full record

ArticleBiological psychology2023

Intergenerational transmission of cognitive control capacity among children at risk for depression.

Akina Umemoto, Zhixin Zhou, Emma M Millon, Christina S Koshy, Sydney M Taylor, Marisa N Spann, Catherine Monk, Rachel Marsh, Anthony J Rosellini, Randy P Auerbach

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Akina UmemotoDepartment of Psychiatry, Columbia University, New York, NY, USA.
Zhixin ZhouDepartment of Counseling and Clinical Psychology, Teachers College, Columbia University, New York, NY, USA.
Emma M MillonDepartment of Psychiatry, Columbia University, New York, NY, USA; Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA.
Christina S KoshyDepartment of Counseling and Clinical Psychology, Teachers College, Columbia University, New York, NY, USA.
Sydney M TaylorDepartment of Psychiatry, Columbia University, New York, NY, USA; Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA.
Marisa N SpannDepartment of Psychiatry, Columbia University, New York, NY, USA; Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA.
Catherine MonkDepartment of Psychiatry, Columbia University, New York, NY, USA; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA; Division of Behavioral Medicine, New York State Psychiatric Institute, New York, NY, USA.
Rachel MarshDepartment of Psychiatry, Columbia University, New York, NY, USA; Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA.
Anthony J RoselliniSchool of Public Health, Boston University, Boston, MA, USA.
Randy P AuerbachDepartment of Psychiatry, Columbia University, New York, NY, USA; Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA; Division of Clinical Developmental Neuroscience, Sackler Institute, New York, NY, USA. Electronic address: rpa2009@cumc.columbia.edu.
Columbia University · USNew York Psychoanalytic Society and Institute · USNew York State Psychiatric InstituteBoston University · US

Funding

INTERGENERATIONAL TRANSMISSION OF DEFICITS IN SELF-REGULATORY CONTROLR01MH117983 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARSH, RACHEL, MONK, CATHERINE E · 2018 to 2022
$4.0M
Social Processing Deficits in Remitted Adolescent DepressionR01MH119771 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI AUERBACH, RANDY PATRICK, SHANKMAN, STEWART AARON · 2020 to 2025
$3.7M
NIMH NIH HHS R01 MH117983NIMH NIH HHS R01 MH119771
6 · The paper itself

Abstract

A maternal history of major depressive disorder (MDD) is a well-known risk factor for depression in offspring. However, the mechanism through which familial risk is transmitted remains unclear. Cognitive control alterations are common in MDD, and thus, the current study investigated whether altered control capacity is transmitted intergenerationally, and whether it then contributes to the developmental pathways through which depression is passed from mothers to children. We recruited children (N = 65) ages 4-10-years-old, of which 47.7 % (n = 31) reported a maternal history of MDD, and their biological mother (N = 65). Children performed a child-friendly Go/NoGo task while electroencephalography (EEG) data were recorded, and mothers performed a Flanker task. Children exhibited heightened sensitivity to error versus correct responses, which was characterized by an error-related negativity (ERN), error positivity (Pe) as well as prominent delta and frontal midline theta (FMT) oscillations. Interestingly, worse maternal performance on the Flanker task associated with an increased Go/NoGo error rate and a smaller ERN and Pe in children. However, there was no association between maternal or child control indices with child depression symptoms. Our results suggest a familial influence of cognitive control capacity in mother-child dyads, but it remains unclear whether this confers risk for depressive symptoms in children. Further research is necessary to determine whether alterations in cognitive control over time may influence symptom development in at-risk children.

Indexed as

Major Depressive DisorderChildChild, PreschoolCognitionDepressionElectroencephalographyEvoked PotentialsFemaleHumansMothersERNError monitoringFrontal midline thetaMaternal depression

Identifiers

PMID37516422
PMCPMC10528753
OpenAlexW4385360517

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.