ReviewReproductive biomedicine online2023
A critical appraisal of studies on endometrial thickness and embryo transfer outcome.
Review in Reproductive biomedicine online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of endometrial thickness on reproductive outcome in fresh and frozen-thawed embryo transfer: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Pooled it
- Causes of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential.Frontiers in endocrinology · 2024Pooled it
- Foundation model-powered deep learning of endometrial histology for predicting the cumulative live birth of an in vitro fertilization cycle.PLOS digital health · 2026Article
- How endometrial thickness affects pregnancy and perinatal outcomes: a retrospective study of 16,566 frozen-thawed single blastocyst transfer cycles.Reproductive biology and endocrinology : RB&E · 2026Article
- Article
- Article
- Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.Frontiers in endocrinology · 2026Article
- Endometrial dysfunction in embryo implantation: from molecular mechanisms to clinical management.Frontiers in reproductive health · 2026Review
- Correlation of MicroRNA-31 with Endometrial Receptivity in Patients with Repeated Implantation Failure ofOrganogenesis · 2025Article
- Prediction of uterine cavity conception environment using two-dimensional transvaginal ultrasound imaging semantic feature-based machine learning: a case-control study.BMC pregnancy and childbirth · 2025Article
- Age does not affect maximal endometrial thickness achieved in frozen embryo transfer cycles: a SARTCORS study.Reproductive biology and endocrinology : RB&E · 2025Article
- Endometrial Infusion with Plasma Rich in Growth Factors (PRGF) in IVF Cycles: Randomized Clinical Trial in Very Thin Endometrium and Observational Uncontrolled Follow-Up After the Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Study on the relationship between endometrial thickness on the hCG day in the progestin-primed ovarian stimulation protocol and pregnancy outcomes in frozen-thawed embryo transfer cycles.Frontiers in endocrinology · 2025Article
- Association of endometrial thickness with live birth rates among women undergoing fresh IVF, FET, and PGT cycles.Frontiers in cell and developmental biology · 2025Article
- Interplay of endocrine and psychological factors in IVF/ICSI outcomes: a prospective cohort analysis.Frontiers in endocrinology · 2025Article
- A Qualitative Exploration of Emotional Experiences in Patients with Thin Endometrium Undergoing Repeated Cancellations of Frozen-Thawed Embryo Transfer Cycles.International journal of women's health · 2025Article
- Analysis of factors influencing clinical pregnancy rates in frozen-thawed embryo transfer cycles.Frontiers in endocrinology · 2025Article
- Subendometrial blood flow detected by Doppler ultrasound associates with pregnancy outcomes of frozen embryo transfer in patients with thin endometrium.Journal of assisted reproduction and genetics · 2024Article
- Impact of elevated serum estradiol levels before progesterone administration on pregnancy outcomes in frozen-thawed embryo transfer for hormone replacement therapy.Reproductive biology and endocrinology : RB&E · 2024Article
- The embryo stage at fresh ET does not affect the cumulative live birth rate in women with a thin endometrium: a retrospective matched-controlled cohort study.Frontiers in endocrinology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A receptive endometrium is required for successful embryo implantation. Endometrial thickness, as measured by ultrasonography, is the most commonly used marker of endometrial receptivity in assisted reproductive technology cycles. Several factors simultaneously affect both endometrial thickness and probability of live birth, including age, oestradiol concentration and oocyte number, among others. Most of the studies investigating a relationship between endometrial thickness and embryo transfer outcomes are retrospective and do not adequately address confounding factors, in addition to other limitations. Despite multiple meta-analyses and studies with large numbers of cycles, controversy still exists. The difference between the results from prospective and retrospective studies is also striking. This article presents a critical appraisal of the studies on endometrial thickness and embryo transfer outcomes in order to highlight methodological issues and how they can be overcome in future studies. Currently available evidence does not seem to support a modification of management just because endometrial thickness is below an arbitrary threshold.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.