ArticleUrolithiasis2023
Effect of outflow resistance on intrarenal pressure at different irrigation rates during ureteroscopy: in vivo evaluation.
Article in Urolithiasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Objective assessment of turbidity during laser lithotripsy: standardization of a dedicated in vitro experimental model.World journal of urology · 2026Article
- Intrarenal pressure response to suction during ureteroscopy with a flexible and navigable suction sheath: in vivo porcine studies.Urolithiasis · 2026Article
- Benchtop comparison of seven ureteroscopes: evaluating physical properties and deflection with flexible and navigable suction access sheaths.BJU international · 2026Article
- Research progress on treating urinary system stones using ureteroscopy combined With a negative-pressure suction sheath.Frontiers in surgery · 2026Review
- Characterization of renal pelvis compliance and outflow resistance during ureteroscopy of the ex-vivo human kidney.American journal of clinical and experimental urology · 2026Article
- Iatrogenic upper urinary tract injuries during ureteroscopy for urolithiasis: a comprehensive review on incidence, mechanisms and preventative strategies.Nature reviews. Urology · 2025Review
- Improved control of renal pelvis pressure using a prototype fluid management system incorporating ureteroscope pressure feedback.Urolithiasis · 2025Article
- Assessing renal tissue temperature changes and perfusion effects during laser activation in an in vivo porcine model.World journal of urology · 2024Article
- Automatic irrigation system with a fiber-optic pressure sensor regulating intrapelvic pressure for flexible ureteroscopy.Scientific reports · 2023Article
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To maintain visualization and control temperature elevation during ureteroscopy, higher irrigation rates are necessary, but this can increase intrarenal pressure (IRP) and lead to adverse effects like sepsis. The IRP is also dependent on outflow resistance but this has not been quantitatively evaluated in a biological system. In this study, we sought to characterize the IRP as a function of irrigation rate in an in vivo porcine model at different outflow resistances. Ureteroscopy was performed in a porcine model with a 9.5 Fr prototype ureteroscope containing a pressure sensor. A modified ureteral access sheath (UAS) (11/13 Fr, 36 cm) was configured to adjust outflow resistance. IRP-irrigation rate curves were generated at four different outlet resistances representing different outflow scenarios. At lower irrigation rates, the pressure change in response to increased irrigation was gradual and non-linear, likely reflecting a "compliant" phase of the renal collecting system. Once IRP reached the range of 35-50 cm H
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