Evidence map›Paper›PMID 37515636›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

The co-existence of peripheral and vestibular neuropathy in diabetes: a cross-sectional study.

Aksayan Arunanthy Mahalingasivam, Asger Krohn Jespersen, Niels Ejskjaer, Dan Dupont Hougaard, Peter Vestergaard, Nicklas Højgaard-Hessellund Rasmussen, Johan Røikjer

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05389566 completednot on this map

Diabetes, Falls, and Fractures

TypeobservationalSponsorAalborg University HospitalRan2022 to 2022Enrolled110ConditionsDiabetic Peripheral Neuropathy, Diabetes, Balance, DistortedArmsQuantative Sensory Testing, NCStat-DPN-Check, Composite Autonomic Symptom Score 31, Computerized dynamic posturography, Video Head Impulse Test
NCT06745544 narecruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes: Protocol for a Randomized Control Trial: DIACTIVE

TypeinterventionalSponsorAalborg University HospitalRan2025 to 2027Enrolled490ConditionsType 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall PreventionArmsRhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Increased fall risk in people with type 2 diabetes and cardiovascular disease: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Pooled it
  3. Associations of video head impulse test and computerized dynamic posturography with self-reported falls and postural control in people with diabetes: an exploratory cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Vestibular function in patients diagnosed with obstructive sleep apnea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Aksayan Arunanthy MahalingasivamDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID http://orcid.org/0000-0003-0406-9702
Asger Krohn JespersenDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID http://orcid.org/0009-0003-3172-5979
Niels EjskjaerSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.
Dan Dupont HougaardBalance & Dizziness Centre, Department of Otolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital, Aalborg, Denmark.
Peter VestergaardSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.
Nicklas Højgaard-Hessellund RasmussenSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.
Johan RøikjerSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark. j.roeikjaer@rn.dk.ORCID http://orcid.org/0000-0002-4578-1328
Steno Diabetes Centers · DKAalborg University · DKAalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiabetic neuropathy can lead to decreased peripheral sensation and motor neuron dysfunction associated with impaired postural control and risk of falling. However, the relationship between decreased peripheral sensation and impaired vestibular function in diabetes mellitus is poorly investigated. Therefore, the aim of this study was to investigate the relationship between peripheral and autonomic measurements of diabetic neuropathy and measurements of vestibular function.

methodsA total of 114 participants with type 1 diabetes (n = 52), type 2 diabetes (n = 51) and controls (n = 11) were included. Vestibular function was evaluated by video head impulse testing. Peripheral neuropathy was assessed by quantitative sensory testing and nerve conduction. Autonomic neuropathy using the COMPASS 31 questionnaire. Data were analyzed according to data type and distribution.

resultsMeasurements of vestibular function did not differ between participants with type 1 diabetes, type 2 diabetes or controls (all p-values above 0.05). Subgrouping of participants according to the involvement of large-, small- or autonomic nerves did not change this outcome. Correlation analyses showed a significant difference between COMPASS 31 and right lateral gain value (ρ = 0.23, p = 0.02,), while no other significant correlations were found.

conclusionDiabetic neuropathy does not appear to impair vestibular function in diabetes, by means of the VOR. CLINICAL TRIALS: NCT05389566, May 25th, 2022.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NeuropathiesVestibular NeuronitisCross-Sectional StudiesHumansDiabetesNeuropathyVestibularVOR

Identifiers

PMID37515636
PMCPMC10796646
OpenAlexW4385380164

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.