Evidence map›Paper›PMID 37515606›Full record

ArticleLasers in medical science2023

The effect of different treatment protocols with diode laser on regeneration in axonetmesis ınjuries of the ınferior alveolar nerve: an animal study.

Kübra Öztürk, Turan Emre Kuzu, Cem A Gürgan, Gözde Özge Önder, Arzu Yay

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Article in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kübra ÖztürkDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey. kbrozturk89@gmail.com.ORCID http://orcid.org/0000-0003-4447-0103
Turan Emre KuzuDepartment of Periodontology, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-9478-1578
Cem A GürganDepartment of Periodontology, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey.ORCID https://orcid.org/0000-0003-0811-008X
Gözde Özge ÖnderDepartment of Histology and Embryology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-0515-9286
Arzu YayDepartment of Histology and Embryology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-0541-8372
Nuh Naci Yazgan University · TRErciyes University · TR

Funding

Nuh Naci Yazgan University Scientific Research Project Coordination Unit 2020-SA.DH-BP/15
6 · The paper itself

Abstract

The inferior alveolar nerve can be damaged during dental procedures, leading to symptoms, such as tingling, numbness, and reduced quality of life. Recovery depends on factors such as medications, surgery, and photobiomodulation therapy. Photobiomodulation therapy has shown the potential to improve nerve function and reduce regeneration time; however, there is no standard treatment protocol yet. This study aimed to examine the effect of diode lasers on nerve regeneration in patients with axonetmesis injuries. In this experiment on animals, Wistar rats' damaged sensory systems were treated with lasers to restore them. Animals were randomly divided into six groups: a sham group, a control group, and four laser treatment groups(1st group: performed every day, 10 sessions; 2nd group: performed every 2 days, 10 sessions; 3rd group: performed every day, 20 sessions; and 4th group: performed every 2 days, 20 sessions). Sensory function was determined using the Semmes-Weinstein monofilament test, which was repeated after the surgical procedure. The results showed that the 20-session group had the best improvement, most closely resembling the group without sensory test damage. The histomorphometric results showed that the number of axons was significantly lower in the group that received 10 daily sessions and in the control group than in the undamaged nerve. Axon diameter was lower in all groups than in the sham group. In conclusion, the remarkable aspect of this study is that consecutive-day 20-session laser treatment showed better improvement than the over-the-day 20-session treatment protocol.

Indexed as

Lasers, SemiconductorLow-Level Light TherapyAnimalsMandibular NerveNerve RegenerationQuality of LifeRatsRats, WistarAxonotmesisInferior alveolar nerveLow-level laser theraphyPhotobiomodulation

Identifiers

PMID37515606
OpenAlexW4385381624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.