ArticleBrain and behavior2023
Health-related quality of life and medication adherence of people living with epilepsy in Pakistan: A cross-sectional study.
Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Health literacy, medication adherence, and quality-of-life scores in Jordanian adults with chronic diseases: a dual analytical study using the long-term conditions questionnaire and the EuroQol five-dimension three-level questionnaire.The Libyan journal of medicine · 2026Article
- The Global Epilepsy Needs Study (GENS): A mixed-methods, multi-country exploration of the unmet psychosocial and everyday needs of people with epilepsy.Epilepsia open · 2026Article
- Awareness, Perceptions, Willingness, and Feasibility of mHealth Apps Among People Living With Epilepsy: Cross-Sectional Questionnaire Study.JMIR formative research · 2025Article
- Impact of gender and side of surgery on cognition, affectivity, and quality of life in patients undergoing temporal lobe epilepsy surgery: a prospective cohort study.Biology of sex differences · 2025Article
- Barriers and facilitators of antiseizure medication adherence: a qualitative study among persons with epilepsy in Pakistan.BMC neurology · 2025Article
- Health literacy, illness perception, and their association with medication adherence in end-stage renal disease.International urology and nephrology · 2025Observational
- Quality of life in adults with refractory epilepsy in Thailand: a multicenter upcountry nationwide study.BMC public health · 2025Article
- Promoting medication compliance in epileptic children: a cross sectional survey.BMC pediatrics · 2024Article
- Knowledge, attitude, and perceptions of healthcare professionals towards complementary and alternative medicine: a cross-sectional survey from twin cities of Pakistan.BMC complementary medicine and therapies · 2023Article
- Health-related quality of life and medication adherence of people living with epilepsy in Pakistan: A cross-sectional study.Brain and behavior · 2023Article
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5 authors.
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Abstract
introductionThe primary purpose of this study was to determine adherence and health-related quality of life (HRQoL) in PWE. Secondary aims were to assess association between adherence and HRQoL and determine predictors of HRQoL in PWE in Pakistan.
methodsA descriptive cross-sectional study was conducted among PWE receiving treatment from two tertiary care hospitals of Pakistan. The HRQoL and adherence were assessed with Urdu versions of Quality of Life in Epilepsy-31 (QOLIE-31), and Medication Adherence Rating Scale (MARS). Relationship between HRQoL and adherence was assessed by Pearson's product-moment correlation coefficient. Forced entry multiple linear models were used to determine relationship of independent variables with HRQoL.
results219 PWE with a mean (±standard deviation) age, 34.18 (± 13.710) years, participated in this study. The overall weighted mean HRQoL score was (51.60 ± 17.10), and mean score for adherence was 6.17 (± 2.31). There was significant association between adherence and HRQoL in PWE (Pearson's correlation = 0.820-0.930; p ≤ .0001). Multiple linear regression found adherence (B = 16.8; p ≤ .0001), male gender (B = 10.0; p = .001), employment status (employed: B = 7.50; p = .030), level of education (Tertiary: B = 0.910; p = .010), duration of epilepsy (>10 years: B = -0.700; p ≤ .0001), and age (≥46 years: B = -0.680; p ≤ .0001), and ASM therapy (polypharmacy: B = 0.430; p = .010) as independent predictors of HRQoL in PWE from Pakistan.
conclusionsThe findings suggest PWE from our center have suboptimal adherence which affects HRQoL. Independent factors such as male gender, employment status and duration of epilepsy are predictors of HRQoL.
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