Evidence map›Paper›PMID 37515265›Full record

ArticleViruses2023

Inflammatory Control of Viral Infection.

Sukanya Chakravarty, Ritu Chakravarti, Saurabh Chattopadhyay

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sukanya ChakravartyMedical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
Ritu ChakravartiPhysiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0000-0003-4680-8374
Saurabh ChattopadhyayMedical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.ORCID 0000-0002-2930-1523
University of Toledo · US

Funding

Anti-inflammatory functions for non-transcriptional IRF3R01AI155545 · NIAID · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI Saurabh Chattopadhyay · 2021 to 2026
$2.2M
Novel antiviral mechanisms of the interferon systemR01AI165521 · NIAID · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI Saurabh Chattopadhyay · 2022 to 2026
$1.7M
NIAID NIH HHS R01 AI155545NIAID NIH HHS R01 AI165521NIH HHS AI155545NIH HHS AI165521
6 · The paper itself

Abstract

Inflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases. Recently, we identified a cellular anti-inflammatory mechanism, RIKA (Repression of IRF3-mediated inhibition of NF-κB activity), which controls viral inflammation and pathogenesis. The RIKA function of IRF3 may be explored further in other inflammatory diseases beyond viral infection.

Indexed as

Signal TransductionVirus DiseasesHumansImmunity, InnateInflammationNF-kappa BNF-kappa Bantiviralinflammationinnate immunityinterferonIRF3NF-κBRIKA

Identifiers

PMID37515265
PMCPMC10383133
OpenAlexW4384929995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.