Evidence map›Paper›PMID 37515249›Full record

ArticleViruses2023

Antiviral Activity of an Indole-Type Compound Derived from Natural Products, Identified by Virtual Screening by Interaction on Dengue Virus NS5 Protein.

Leidy Lorena García-Ariza, Natalia González-Rivillas, Cindy Johanna Díaz-Aguirre, Cristian Rocha-Roa, Leonardo Padilla-Sanabria, Jhon Carlos Castaño-Osorio

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leidy Lorena García-ArizaGrupo de Inmunología Molecular GYMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0003-1994-0775
Natalia González-RivillasGrupo de Inmunología Molecular GYMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0003-0996-743X
Cindy Johanna Díaz-AguirreGrupo de Inmunología Molecular GYMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0003-4934-195X
Cristian Rocha-RoaGrupo de Parasitología Molecular GEPAMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0002-4602-6121
Leonardo Padilla-SanabriaGrupo de Inmunología Molecular GYMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0001-5811-2791
Jhon Carlos Castaño-OsorioGrupo de Inmunología Molecular GYMOL, Universidad del Quindío, Armenia 630001, Quindío, Colombia.ORCID 0000-0002-7639-3053
University of Quindío · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is an acute febrile illness caused by the Dengue virus (DENV), with a high number of cases worldwide. There is no available treatment that directly affects the virus or the viral cycle. The objective of this study was to identify a compound derived from natural products that interacts with the NS5 protein of the dengue virus through virtual screening and evaluate its

Indexed as

Biological ProductsDengueDengue VirusAntiviral AgentsHumansMolecular Docking SimulationRNA, ViralViral Nonstructural ProteinsVirus ReplicationAntiviral AgentsBiological ProductsRNA, ViralViral Nonstructural Proteinsantiviral activityDengue virusnatural compoundsNS5 protein

Identifiers

PMID37515249
PMCPMC10384440
OpenAlexW4384557352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.