Evidence map›Paper›PMID 37515240›Full record

ArticleViruses2023

COVID-19 and Thromboembolic Events in the Pandemic and Pre-Pandemic Era: A Pediatric Cohort.

Chiara Rubino, Camilla Bechini, Mariangela Stinco, Donatella Lasagni, Giuseppe Indolfi, Sandra Trapani

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chiara RubinoPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.
Camilla BechiniPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.ORCID 0009-0001-0877-3599
Mariangela StincoPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.
Donatella LasagniPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.
Giuseppe IndolfiPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0003-3830-9823
Sandra TrapaniPediatric Unit, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0003-1105-1500
Meyer Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) have been variably associated with thromboembolic events (TEs) in children. The aim of our study was to assess the prevalence of TEs in children hospitalized during a five-year period in a tertiary pediatric hospital, particularly in patients with COVID-19 and MIS-C. Overall, 38 patients were discharged with the diagnosis of TE: 20 in the pre-pandemic and 18 in the pandemic period. The prevalence of TEs was the same (0.08%) in the pre-pandemic and pandemic periods. The occurrence of TEs was higher in patients with COVID-19 or MIS-C (6/517, 1.16%) when compared to children without these conditions in the pandemic and in the pre-pandemic periods. The prevalence of TEs in children with MIS-C was significantly higher than the prevalence in patients with COVID-19. Five out of six of the patients with COVID-19 or MIS-C developing a TE had at least one predisposing factor to thrombosis. In conclusion, our study shows an increased prevalence of TEs in children hospitalized with COVID-19 or MIS-C, if compared to children without COVID-19 or MIS-C in the pandemic period and in the pre-pandemic period. The prevalence of TEs was significantly higher in patients with MIS-C.

Indexed as

COVID-19PandemicsChildHumansPatient DischargeSystemic Inflammatory Response SyndromechildrenCOVID-19multisystem inflammatory systemthrombosis

Identifiers

PMID37515240
PMCPMC10383326
OpenAlexW4384557614

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.