Evidence map›Paper›PMID 37515222›Full record

ArticleViruses2023

Unusual Canine Distemper Virus Infection in Captive Raccoons (

Adrian Constantin Stancu, Octavian Sorin Voia, Oana Maria Boldura, Sorin Aurelian Pasca, Iasmina Luca, Anca Sofiana Hulea, Oana Roxana Ivan, Alina Andreea Dragoescu, Bianca Cornelia Lungu, Ioan Hutu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Adrian Constantin StancuFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.
Octavian Sorin VoiaFaculty of Animal Resources Bioengineering, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.
Oana Maria BolduraFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.ORCID 0000-0001-9335-4462
Sorin Aurelian PascaFaculty of Veterinary Medicine, University of Life Sciences, 700506 Iasi, Romania.ORCID 0000-0002-9519-8122
Iasmina LucaFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.ORCID 0000-0002-1153-6498
Anca Sofiana HuleaFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.ORCID 0000-0001-7197-6682
Oana Roxana IvanFaculty of Letters, West University, 300223 Timisoara, Romania.
Alina Andreea DragoescuFaculty of Agriculture, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.
Bianca Cornelia LunguFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.
Ioan HutuFaculty of Veterinary Medicine, Horia Cernescu Research Unit, University of Life Sciences "King Michael I", 300645 Timisoara, Romania.ORCID 0000-0002-0594-2852
West University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine morbillivirus, also known as canine distemper virus (CDV), is the causative agent of canine distemper (CD), which is a serious contagious disease of canines, large felids, and, occasionally, raccoons. This study included seven raccoons from the Timisoara Zoological Garden, Romania. CDV was detected using RT-qPCR on blood samples, but several other exams were also performed-clinical, bacteriological, immunohistochemistry (IHC) and histopathology, toxicological screening, and necropsy-which confirmed CDV infection. Severe digestive disorders (diarrhea and frequent hematemesis) were observed. The necropsy findings included pseudo membranous gastroenteritis, congestion, and pulmonary edema in two raccoons. Immunohistochemistry showed immunolabeled CDV antigenantibodies on the viral nucleocapsid. Histopathology revealed lymphocyte depletion in mesenteric lymphnodes and intranuclear and intracytoplasmic inclusions in the enterocytes of the small intestine. Based on the RT-qPCR assay, laboratory tests, and the lesions observed, it was established that the raccoons were infected with CDV, which was the cause of death in two cases. The results from the necropsy, histology, and immunohistochemistry in the raccoons are comparable with reported CDV lesions in dogs. In conclusion, several exams may be performed to establish the etiology of possible interspecific viral infection, but only very specific exams can identify aCDV infection. Laboratory analyses must be completed by RT-qPCR assay or IHC to establish infection with uncommon viruses in raccoons with high accuracy.

Indexed as

DistemperDistemper Virus, CaninePulmonary EdemaAnimalsDogsImmunohistochemistryRaccoonscanine distemperCanine morbillivirushistopathologyimmunohistochemistryraccoonsRT-qPCR detection

Identifiers

PMID37515222
PMCPMC10383698
OpenAlexW4384131382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.