Evidence map›Paper›PMID 37515112›Full record

ArticleViruses2023

Antiviral Activity of an Endogenous Parvoviral Element.

Angelica Bravo, Leandro Fernández-García, Rodrigo Ibarra-Karmy, Gonzalo A Mardones, Luis Mercado, Fernando J Bustos, Robert J Gifford, Gloria Arriagada

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Angelica BravoInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370071, Chile.ORCID 0009-0006-1677-1258
Leandro Fernández-GarcíaInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370071, Chile.
Rodrigo Ibarra-KarmyInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370071, Chile.
Gonzalo A MardonesFacultad de Medicina y Ciencia, Universidad San Sebastián, Valdivia 5110466, Chile.ORCID 0000-0001-9390-5893
Luis MercadoInstituto de Biología, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.
Fernando J BustosInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370071, Chile.ORCID 0000-0002-0487-7032
Robert J GiffordCentre for Virus Research, MRC-University of Glasgow, 464 Bearsden Rd, Bearsden, Glasgow G61 1QH, UK.ORCID 0000-0003-4028-9884
Gloria ArriagadaInstituto de Ciencias Biomedicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370071, Chile.ORCID 0000-0002-9935-0451
Universidad Andrés Bello · CLMRC University of Glasgow Centre for Virus Research · GBPontificia Universidad Católica de Valparaíso · CLSan Sebastián University · CL

Funding

Medical Research Council MC_UU_12014/12
6 · The paper itself

Abstract

Endogenous viral elements (EVEs) are genomic DNA sequences derived from viruses. Some EVEs have open reading frames (ORFs) that can express proteins with physiological roles in their host. Furthermore, some EVEs exhibit a protective role against exogenous viral infection in their host. Endogenous parvoviral elements (EPVs) are highly represented in mammalian genomes, and although some of them contain ORFs, their function is unknown. We have shown that the locus

Indexed as

Parvoviridae InfectionsParvovirusVirusesAnimalsAntiviral AgentsGenomeMammalsMiceAntiviral Agentsendogenous viral elementsevolutionimmunitypaleovirologyparvovirus

Identifiers

PMID37515112
PMCPMC10384997
OpenAlexW4382137042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.