Evidence map›Paper›PMID 37515095›Full record

ArticleViruses2023

High-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan.

Ainur Sanaubarova, Emma Pujol-Hodge, Natalya Dzissyuk, Philippe Lemey, Sten H Vermund, Andrew J Leigh Brown, Syed Ali

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ainur SanaubarovaDepartment of Biomedical Sciences, Nazarbayev School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Emma Pujol-HodgeSchool of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK.ORCID 0000-0001-8861-6608
Natalya DzissyukKazakh Scientific Center of Dermatology and Infectious Diseases, Almaty 010000, Kazakhstan.
Philippe LemeyDepartment of Microbiology and Immunology, Rega Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.
Sten H VermundDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, USA.ORCID 0000-0001-7289-8698
Andrew J Leigh BrownSchool of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK.
Syed AliDepartment of Biomedical Sciences, Nazarbayev School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI E. Jennifer Edelman · 2001 to 2026
$48.5M
Phylodynamic Analysis of HIV Transmission Clusters in Kazakhstan for Targeted InterventionsR03DA052179 · NIDA · YALE UNIVERSITY · PI ALI, SYED, VERMUND, STEN H. · 2020 to 2021
$145k
NCATS NIH HHS UL1 TR001863NIDA NIH HHS R03 DA052179NIMH NIH HHS P30 MH062294Wellcome TrustWellcome Trust 222329/Z/21/Z
6 · The paper itself

Abstract

HIV incidence in Kazakhstan increased by 73% between 2010 and 2020, with an estimated 35,000 people living with HIV (PLHIV) in 2020. The development of antiretroviral drug resistance is a major threat to effective antiretroviral therapy (ART), yet studies on the prevalence of drug resistance in Kazakhstan are sparse. In this study on the molecular epidemiology of HIV in Kazakhstan, we analyzed 968 partial HIV-1

Indexed as

Anti-HIV AgentsHIV-1HIV InfectionsDrug Resistance, ViralGenotypeHumansKazakhstanMutationPhylogenyAnti-HIV AgentsA6antiretroviral drug resistanceCentral AsiaCRF02_AGDRMsHIVKazakhstanmolecular epidemiologyphylogenetics

Identifiers

PMID37515095
PMCPMC10384832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.