Evidence map›Paper›PMID 37515002›Full record

ArticleVaccines2023

Coronavirus Disease 2019 (COVID-19) Reinfection Rates in Malawi: A Possible Tool to Guide Vaccine Prioritisation and Immunisation Policies.

Master R O Chisale, Frank Watson Sinyiza, Paul Uchizi Kaseka, Chikondi Sharon Chimbatata, Balwani Chingatichifwe Mbakaya, Tsung-Shu Joseph Wu, Billy Wilson Nyambalo, Annie Chauma-Mwale, Ben Chilima, Kwong-Leung Joseph Yu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Master R O ChisaleFaculty of Sciences, Technology and Innovations, Biological Sciences, Mzuzu University, P/Bag 201 Luwinga, Mzuzu, Malawi.ORCID 0000-0002-8301-6184
Frank Watson SinyizaMzuzu Central Hospital, Ministry of Health, P/Bag 209 Luwinga, Mzuzu, Malawi.ORCID 0000-0002-5009-4012
Paul Uchizi KasekaMzuzu Central Hospital, Ministry of Health, P/Bag 209 Luwinga, Mzuzu, Malawi.ORCID 0000-0002-6651-8000
Chikondi Sharon ChimbatataMzuzu Central Hospital, Ministry of Health, P/Bag 209 Luwinga, Mzuzu, Malawi.
Balwani Chingatichifwe MbakayaDepartment of Public Health, University of Livingstonia, Mzuzu 00265, Malawi.ORCID 0000-0002-4705-9064
Tsung-Shu Joseph WuResearch Department, Luke International, Mzuzu P.O. Box 1088, Malawi.ORCID 0000-0001-6155-9340
Billy Wilson NyambaloPublic Health Institute of Malawi, Ministry of Health, Lilongwe 00265, Malawi.
Annie Chauma-MwalePublic Health Institute of Malawi, Ministry of Health, Lilongwe 00265, Malawi.
Ben ChilimaPublic Health Institute of Malawi, Ministry of Health, Lilongwe 00265, Malawi.
Kwong-Leung Joseph YuResearch Department, Luke International, Mzuzu P.O. Box 1088, Malawi.
Alfred Bornwell KayiraMzuzu Central Hospital, Ministry of Health, P/Bag 209 Luwinga, Mzuzu, Malawi.
Mzuzu University · MWPublic Health Institute of Malawi · MWUniversity of Livingstonia · MW

Funding

Luke International Malawi PS-IR-110001
6 · The paper itself

Abstract

As the fight against the COVID-19 pandemic continues, reports indicate that the global vaccination rate is still far below the target. Understanding the levels of reinfection may help refocus and inform policymakers on vaccination. This retrospective study in Malawi included individuals and patients who tested for COVID-19 infections via reverse transcriptase polymerase chain reaction (rt-PCR) from the data at the Public Health Institute of Malawi (PHIM). We included all data in the national line list from April 2020 to March 2022. Upon review of 47,032 records, 45,486 were included with a reported 82 (0.18) reinfection representing a rate of 0.55 (95% CI: 0.44-0.68) per 100,000 person-days of follow-up. Most reinfections occurred in the first 90 to 200 days following the initial infection, and the median time to reinfection was 175 days (IQR: 150-314), with a range of 90-563 days. The risk of reinfection was highest in the immediate 3 to 6 months following the initial infection and declined substantially after that, and age demonstrated a significant association with reinfection. Estimating the burden of SARS-CoV-2 reinfections, a specific endurance of the immunity naturally gained, and the role played by risk factors in reinfections is relevant for identifying strategies to prioritise vaccination.

Indexed as

COVID-19immune responseimmunizationsreinfectionSARS-CoV-2vaccinations

Identifiers

PMID37515002
PMCPMC10383452
OpenAlexW4382752167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.