Evidence map›Paper›PMID 37515001›Full record

ArticleVaccines2023

SARS-CoV-2 Antibody Dynamics after COVID-19 Vaccination and Infection: A Real-World Cross-Sectional Analysis.

Ritthideach Yorsaeng, Kamolthip Atsawawaranunt, Nungruthai Suntronwong, Sitthichai Kanokudom, Jira Chansaenroj, Suvichada Assawakosri, Pornjarim Nilyanimit, Ratchadawan Aeemjinda, Nongkanok Khanarat, Lakkhana Wongsrisang and 9 more

Abstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. An overview of HLA variants in COVID-19 vaccine-induced autoimmunity.International journal of molecular epidemiology and genetics · 2025
    Review
  5. Mechanistic models of humoral kinetics following COVID-19 vaccination.Journal of the Royal Society, Interface · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ritthideach YorsaengCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.ORCID 0000-0001-9391-663X
Kamolthip AtsawawaranuntInstitute for Urban Disease Control and Prevention, Department of Disease Control, Ministry of Public Health, Anusawari, Bang Khen, Bangkok 10220, Thailand.
Nungruthai SuntronwongCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Sitthichai KanokudomCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.ORCID 0000-0001-9482-6353
Jira ChansaenrojCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Suvichada AssawakosriCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Pornjarim NilyanimitCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.ORCID 0000-0003-2250-0017
Ratchadawan AeemjindaCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Nongkanok KhanaratCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Lakkhana WongsrisangCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Chompoonut AuphimaiCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Preeyaporn VichaiwattanaCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Sirapa KlinfuengCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Thanunrat ThongmeeCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Donchida SrimuanCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Thaksaporn ThatsanathornCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Natthinee SudhinarasetCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Nasamon WanlapakornCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Yong PoovorawanCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.ORCID 0000-0002-2337-6807

Funding

BJC Big C FoundationHealth Systems Research InstituteMK restaurant Group Aunt Thongkum FoundationNational Research Council of ThailandRatchadapisek Somphot Fund for Postdoctoral Fellowship, Chulalongkorn Universitythe Center of Excellence in Clinical Virology, Chulalongkorn University, and the King Chulalongkorn Memorial Hospital
6 · The paper itself

Abstract

The Coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), continues to surge despite the widespread use of vaccination. In Thailand, more than 77% and 39% of the population received two doses and three doses of COVID-19 vaccines as of December 2022, respectively. In addition, during the Omicron predominant period in 2022, more than 70% of Thai individuals have been infected. To gain comprehensive insight into SARS-CoV-2 antibody dynamics following vaccination or following vaccination and infection (hybrid immunity), we performed a cross-sectional analysis of sera samples from individuals who received COVID-19 vaccination and/or have been infected with COVID-19 in Thailand between January 2021 and December 2022. A total of 4126 samples were collected. Humoral immunity was evaluated by quantifying the immunoglobulin (including IgG, IgM, and IgA isotypes) specific to the SARS-CoV-2 receptor-binding domain (RBD) or Ig anti-RBD. The results showed that individuals who received two-dose vaccination alone had lower levels of Ig anti-RBD, which rapidly waned over time. To restore the waning antibody, a third dose vaccination is recommended for uninfected individuals who have only received 2 doses.

Indexed as

anti-RBDboosterCOVID-19humoral immunityinfectionSARS-CoV-2vaccine

Identifiers

PMID37515001
PMCPMC10384814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.