Evidence map›Paper›PMID 37514997›Full record

ReviewVaccines2023

The End or a New Era of Development of SARS-CoV-2 Virus: Genetic Variants Responsible for Severe COVID-19 and Clinical Efficacy of the Most Commonly Used Vaccines in Clinical Practice.

Dimitrina Miteva, Meglena Kitanova, Hristiana Batselova, Snezhina Lazova, Lyubomir Chervenkov, Monika Peshevska-Sekulovska, Metodija Sekulovski, Milena Gulinac, Georgi V Vasilev, Luchesar Tomov and 1 more

Abstract readReview
In one paragraph

Review in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dimitrina MitevaDepartment of Genetics, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov str., 1164 Sofia, Bulgaria.ORCID 0000-0002-5931-2426
Meglena KitanovaDepartment of Genetics, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov str., 1164 Sofia, Bulgaria.ORCID 0000-0002-6730-7387
Hristiana BatselovaDepartment of Epidemiology and Disaster Medicine, University Hospital "Saint George", Medical University, 6000 Plovdiv, Bulgaria.
Snezhina LazovaPediatric Department, University Hospital "N. I. Pirogov," 21 "General Eduard I. Totleben" Blvd, 1606 Sofia, Bulgaria.ORCID 0000-0002-5884-7760
Lyubomir ChervenkovDepartment of Diagnostic Imaging, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-8380-5992
Monika Peshevska-SekulovskaDepartment of Gastroenterology, University Hospital Lozenetz, 1407 Sofia, Bulgaria.ORCID 0000-0002-8468-0132
Metodija SekulovskiMedical Faculty, Sofia University St. Kliment Ohridski, 1407 Sofia, Bulgaria.ORCID 0000-0001-8374-7756
Milena GulinacDepartment of General and Clinical Pathology, Medical University of Plovdiv, Bul. Vasil Aprilov 15A, 4000 Plovdiv, Bulgaria.
Georgi V VasilevClinic of Endocrinology and Metabolic Disorders, UMHAT "Sv. Georgi", 4000 Plovdiv, Bulgaria.ORCID 0000-0002-3280-5060
Luchesar TomovDepartment of Informatics, New Bulgarian University, Montevideo 21 str., 1618 Sofia, Bulgaria.ORCID 0000-0003-1902-6473
Tsvetelina VelikovaMedical Faculty, Sofia University St. Kliment Ohridski, 1407 Sofia, Bulgaria.ORCID 0000-0002-0593-1272

Funding

the European Union-NextGenerationEU, through the National Recovery and Resilience Plan of the Republic of Bulgaria, project № BG-RRP-2.004-0008-C01
6 · The paper itself

Abstract

Although the chief of the World Health Organization (WHO) has declared the end of the coronavirus disease 2019 (COVID-19) as a global health emergency, the disease is still a global threat. To be able to manage such pandemics in the future, it is necessary to develop proper strategies and opportunities to protect human life. The data on the SARS-CoV-2 virus must be continuously analyzed, and the possibilities of mutation and the emergence of new, more infectious variants must be anticipated, as well as the options of using different preventive and therapeutic techniques. This is because the fast development of severe acute coronavirus 2 syndrome (SARS-CoV-2) variants of concern have posed a significant problem for COVID-19 pandemic control using the presently available vaccinations. This review summarizes data on the SARS-CoV-2 variants that are responsible for severe COVID-19 and the clinical efficacy of the most commonly used vaccines in clinical practice. The consequences after the disease (long COVID or post-COVID conditions) continue to be the subject of studies and research, and affect social and economic life worldwide.

Indexed as

COVID-19effectivenessefficacysafetySARS-CoV-2 variantsvaccines

Identifiers

PMID37514997
PMCPMC10385722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.