Evidence map›Paper›PMID 37514831›Full record

ArticleSensors (Basel, Switzerland)2023

An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts.

Niall Holmes, Richard Bowtell, Matthew J Brookes, Samu Taulu

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Potential ofEpilepsia open · 2025
    Article
  4. Article
  5. SPM-30 years and beyond.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Review
  6. Wearable Magnetoencephalography in a Lightly Shielded Environment.IEEE transactions on bio-medical engineering · 2025
    Article
  7. Article
  8. Determining sensor geometry and gain in a wearable MEG system.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Niall HolmesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.ORCID 0000-0002-0561-8366
Richard BowtellSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Samu TauluDepartment of Physics, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-6164-3366

Funding

Next generation Magnetoencephalography for human social neuroscienceR01EB028772 · NIBIB · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LACONTE, STEPHEN M, MONTAGUE, P READ · 2020 to 2023
$2.4M
Spatial-frequency decompositions for enhancement of source reconstruction resolution in MEGR21EB033577 · NIBIB · UNIVERSITY OF WASHINGTON · PI TAULU, SAMU · 2022 to 2024
$622k
NIBIB NIH HHS R01 EB028772NIBIB NIH HHS R21 EB033577NIH HHS R01EB028772NIH HHS R21EB033577Wellcome Trust 203257/B/16/ZWellcome Trust 203257/Z/16/Z
6 · The paper itself

Abstract

The signal space separation (SSS) method is routinely employed in the analysis of multichannel magnetic field recordings (such as magnetoencephalography (MEG) data). In the SSS method, signal vectors are posed as a multipole expansion of the magnetic field, allowing contributions from sources internal and external to a sensor array to be separated via computation of the pseudo-inverse of a matrix of the basis vectors. Although powerful, the standard implementation of the SSS method on MEG systems based on optically pumped magnetometers (OPMs) is unstable due to the approximate parity of the required number of dimensions of the SSS basis and the number of channels in the data. Here we exploit the hierarchical nature of the multipole expansion to perform a stable, iterative implementation of the SSS method. We describe the method and investigate its performance via a simulation study on a 192-channel OPM-MEG helmet. We assess performance for different levels of truncation of the SSS basis and a varying number of iterations. Results show that the iterative method provides stable performance, with a clear separation of internal and external sources.

Indexed as

magnetoencephalographyMEG analysisoptically pumped magnetometerSSS

Identifiers

PMID37514831
PMCPMC10385807

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.