Evidence map›Paper›PMID 37514752›Full record

ArticleSensors (Basel, Switzerland)2023

Quantitative Assessment on Optical Properties as a Basis for Bioluminescence Imaging: An Experimental and Numerical Approach to the Transport of Optical Photons in Phantom Materials.

Tim Karstens, Theresa Staufer, Rasmus Buchin, Florian Grüner

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tim KarstensInstitut für Experimentalphysik and Center for Free-Electron Laser Science (CFEL), Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.
Theresa StauferInstitut für Experimentalphysik and Center for Free-Electron Laser Science (CFEL), Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.ORCID 0000-0001-6658-5775
Rasmus BuchinInstitut für Experimentalphysik and Center for Free-Electron Laser Science (CFEL), Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.
Florian GrünerInstitut für Experimentalphysik and Center for Free-Electron Laser Science (CFEL), Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioluminescence imaging (BLI) is a widely used technique in preclinical scientific research, particularly in the development of mRNA-based medications and non-invasive tumor diagnostics. It has become an essential tool in current science. However, the current state of bioluminescence imaging is primarily qualitative, making it challenging to obtain quantitative measurements and to draw accurate conclusions. This fact is caused by the unique properties of optical photons and tissue interactions. In this paper, we propose an experimental setup and Geant4-simulations to gain a better understanding of the optical properties and processes involved in bioluminescence imaging. Our goal is to advance the field towards more quantitative measurements. We will discuss the details of our experimental setup, the data we collected, the outcomes of the Geant4-simulations, and additional information on the underlying physical processes.

Indexed as

Diagnostic ImagingPhotonsLuminescent MeasurementsMonte Carlo MethodPhantoms, Imagingbioluminescence imagingGeant4 simulationsoptical physicsoptical propertiessoft tissue

Identifiers

PMID37514752
PMCPMC10383780

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.