Hadamard Transform Ion Mobility Spectrometry Based on Matrix Encoding Modulation.

Ke Chen, Lingfeng Li, Peng Li

Open access · goldAbstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.4field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ke ChenSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.

Lingfeng LiSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.

Peng LiSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.ORCID 0000-0002-6423-2981

Soochow University · CN

Funding

National High Level Hospital Clinical Research Funding BJ-2022-095National Natural Science Foundation of China 21904091National Natural Science Foundation of China 52205598National Natural Science Foundation of China 62001318

6 · The paper itself

Abstract

Ion mobility spectrometry (IMS) has been widely used for the on-site detection of trace chemicals, but continue to suffer from a low duty cycle of ion injection. The Hadamard transform ion mobility spectrometry (HT-IMS) technique was employed to address the problem with increased signal-to-noise ratio (SNR). However, in this work, through simulation, a certain deviation between the mathematical principle of Hadamard transform and actual data collection process was found, which resulted in a distortion of the baseline in the spectrum. The reason behind this problem was analyzed and a novel IMS based on Sylvester-type Hadamard matrix encoding modulation (Sylvester-HT-IMS), together with a set of date collection and processing technique, was proposed. Sylvester-HT-IMS offered much improved quality of deconvoluted spectrum and overall performance in the simulation. In experimental verification, with reactant ions and product ions characterized, Sylvester-HT-IMS showed improved SNR and ion discrimination over both conventional signal-averaged IMS (SA-IMS) and HT-IMS, providing an alternative method for multiplexed IMS.

Indexed as

Hadamard transformIMSmatrixSNR

Identifiers

PMID37514561

DOI10.3390/s23146267

PMCPMC10383960

OpenAlexW4383912306

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.