Evidence map›Paper›PMID 37514474›Full record

ReviewPolymers2023

Polymer-Based Hydrogel Loaded with Honey in Drug Delivery System for Wound Healing Applications.

Siti Nor Najihah Yasin, Zulfahmi Said, Nadia Halib, Zulaiha A Rahman, Noor Izzati Mokhzani

Abstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Frontiers in pharmacology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Applications and prospects of biomaterials in diabetes management.Frontiers in bioengineering and biotechnology · 2025
    Review
  13. Review
  14. Closing Editorial.Polymers · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siti Nor Najihah YasinDepartment of Basic Sciences and Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia.
Zulfahmi SaidDepartment of Basic Sciences and Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia.ORCID 0000-0002-6917-4354
Nadia HalibDepartment of Basic Sciences and Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia.ORCID 0000-0002-3709-7753
Zulaiha A RahmanDepartment of Basic Sciences and Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia.
Noor Izzati MokhzaniDepartment of Basic Sciences and Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur 55100, Malaysia.

Funding

Fundamental Research Grant Scheme (FRGS) FRGS/1/2020/STG05/USIM/03/1
6 · The paper itself

Abstract

Excellent wound dressings should have crucial components, including high porosity, non-toxicity, high water absorption, and the ability to retain a humid environment in the wound area and facilitate wound healing. Unfortunately, current wound dressings hamper the healing process, with poor antibacterial, anti-inflammatory, and antioxidant activity, frequent dressing changes, low biodegradability, and poor mechanical properties. Hydrogels are crosslinked polymer chains with three-dimensional (3D) networks that have been applicable as wound dressings. They could retain a humid environment on the wound site, provide a protective barrier against pathogenic infections, and provide pain relief. Hydrogel can be obtained from natural, synthetic, or hybrid polymers. Honey is a natural substance that has demonstrated several therapeutic efficacies, including anti-inflammatory, antibacterial, and antioxidant activity, which makes it beneficial for wound treatment. Honey-based hydrogel wound dressings demonstrated excellent characteristics, including good biodegradability and biocompatibility, stimulated cell proliferation and reepithelization, inhibited bacterial growth, and accelerated wound healing. This review aimed to demonstrate the potential of honey-based hydrogel in wound healing applications and complement the studies accessible regarding implementing honey-based hydrogel dressing for wound healing.

Indexed as

honeyhydrogelnatural polymersynthetic polymerwound dressingswound healing

Identifiers

PMID37514474
PMCPMC10383286

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.